User profiles for Y.-H. Ko

Young Ho Ko

Institute for basic science
Verified email at ibs.re.kr
Cited by 10232

Functionalized cucurbiturils and their applications

K Kim, N Selvapalam, YH Ko, KM Park… - Chemical Society …, 2007 - pubs.rsc.org
Cucurbit[n]uril (CB[n], n = 5–10), a new family of molecular hosts comprising n glycoluril
units, have gained much attention in the new millennium for their exceptional molecular …

Hexokinase-2 bound to mitochondria: cancer's stygian link to the “Warburg Effect” and a pivotal target for effective therapy

SP Mathupala, YH Ko, PL Pedersen - Seminars in cancer biology, 2009 - Elsevier
The most common metabolic hallmark of malignant tumors, ie, the “Warburg effect” is their
propensity to metabolize glucose to lactic acid at a high rate even in the presence of oxygen. …

Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria

SP Mathupala, YH Ko, PL Pedersen - Oncogene, 2006 - nature.com
… However, recent studies with ANT knockout mice have indicated that MPT can occur even
in the absence of ANTs. Thus, the exact role of these translocators in facilitating apoptosis …

Extranodal natural killer T-cell lymphoma, nasal-type: a prognostic model from a retrospective multicenter study

J Lee, C Suh, YH Park, YH Ko, SM Bang… - Journal of clinical …, 2006 - ascopubs.org
Purpose Patients with natural killer T (NK/T) -cell lymphomas have poor survival outcome,
and for this condition there is no optimal therapy. The purpose of this study was to design a …

A synthetic host-guest system achieves avidin-biotin affinity by overcoming enthalpy–entropy compensation

MV Rekharsky, T Mori, C Yang, YH Ko… - Proceedings of the …, 2007 - National Acad Sciences
The molecular host cucurbit[7]uril forms an extremely stable inclusion complex with the
dicationic ferrocene derivative bis(trimethylammoniomethyl)ferrocene in aqueous solution. The …

Complexation of ferrocene derivatives by the cucurbit [7] uril host: a comparative study of the cucurbituril and cyclodextrin host families

…, K Moon, SH Park, H Chun, YH Ko… - Journal of the …, 2005 - ACS Publications
The formation of inclusion complexes between cucurbit[7]uril (CB[7]) and ferrocene and its
derivatives has been investigated. The X-ray crystal structure of the 1:1 inclusion complex …

Effect of a commercial essential oil on growth performance, digestive enzyme activity and intestinal microflora population in broiler chickens

IS Jang, YH Ko, SY Kang, CY Lee - Animal Feed Science and Technology, 2007 - Elsevier
The present study was designed to evaluate whether a blend of essential oils (EO) extracted
from herbs could affect growth performance, digestive enzymes and antimicrobial activity of …

Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP

YH Ko, BL Smith, Y Wang, MG Pomper, DA Rini… - Biochemical and …, 2004 - Elsevier
A common feature of many advanced cancers is their enhanced capacity to metabolize
glucose to lactic acid. In a challenging study designed to assess whether such cancers can be …

The impact of Epstein-Barr virus status on clinical outcome in diffuse large B-cell lymphoma

S Park, J Lee, YH Ko, A Han, HJ Jun… - Blood, The Journal …, 2007 - ashpublications.org
To define prognostic impact of Epstein-Barr virus (EBV) infection in diffuse large B-cell
lymphoma (DLBCL), we investigated EBV status in patients with DLBCL. In all, 380 slides from …

Phase II trial of concurrent radiation and weekly cisplatin followed by VIPD chemotherapy in newly diagnosed, stage IE to IIE, nasal, extranodal NK/T-Cell Lymphoma …

…, GW Lee, KM Kang, HS Eom, HR Pyo, YC Ahn, YH Ko… - 2009 - ir.ymlib.yonsei.ac.kr
PURPOSE: On the basis of the benefits of frontline radiation in early-stage, extranodal,
natural killer (NK)/T-cell lymphoma (ENKTL), we conducted a phase II trial of concurrent …