Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity

…, K Toga, S Tochizawa, Y Inoue, Y Kimura… - Biochemical …, 2000 - Elsevier
The inhibitory potential of novel anti-platelet aggregatory cilostamide analogues on
phosphodiesterase (PDE) isozyme activities was investigated with recombinant PDE isozymes …

Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis

…, Y Lin, T Okamoto, M Araki, Y Kimura… - Proceedings of the …, 2021 - National Acad Sciences
Multiple sclerosis (MS), a putative autoimmune disease of the central nervous system (CNS),
commonly presents as relapsing-remitting MS (RRMS), characterized by recurrent …

Microcystins from Anabaena flos-aquae NRC 525-17

K Harada, K Ogawa, Y Kimura, H Murata… - Chemical Research …, 1991 - ACS Publications
Anabaena flos-aquae NRC 525-17 produces a very potent neurotoxin, anatoxin-a (s). During
isolation of the neurotoxin, we found that the strain contains four other toxic compounds …

Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets

T Sudo, H Ito, Y Kimura - Platelets, 2003 - Taylor & Francis
Vasodilator-stimulated phosphoprotein (VASP) is a regulator of actin dynamics in platelets
and a common substrate of both cAMP- and cGMP-dependent protein kinases (PKA and PKG)…

Enzyme immunoassay detection of platelet-derived microparticles and RANTES in acute coronary syndrome

…, S Saito, K Osumi, Y Ozeki, Y Kimura - Thrombosis and …, 2003 - thieme-connect.com
Platelet-derived microparticles (PDMPs) are produced by platelet activation or physical
stimulation under various conditions. To evaluate changes in platelet and chemokine function in …

Usefulness of SWI for the detection of iron in the motor cortex in amyotrophic lateral sclerosis

Y Adachi, N Sato, Y Saito, Y Kimura… - Journal of …, 2015 - Wiley Online Library
PURPOSE The purpose of the present retrospective study was to evaluate the sensitivity of
susceptibility‐weighted imaging (SWI) compared to conventional spin‐echo T2‐weighted …

Neuroimaging-based brain-age prediction in diverse forms of epilepsy: a signature of psychosis and beyond

D Sone, I Beheshti, N Maikusa, M Ota, Y Kimura… - Molecular …, 2021 - nature.com
Epilepsy is a diverse brain disorder, and the pathophysiology of its various forms and
comorbidities is largely unknown. A recent machine learning method enables us to estimate an …

Analysis of chatter in tandem cold rolling mills

Y Kimura, Y Sodani, N Nishiura, N Ikeuchi… - ISIJ …, 2003 - jstage.jst.go.jp
Secondly, a simple self-exited vibration model is proposed and the stability index is proposed
for further understanding of the phenomena. An analytical approach is made to predict the …

Potentiation of anti-platelet aggregating activity of cilostazol with vascular endothelial cells

…, K Kawamura, S Kato, F Unemi, Y Kimura - Thrombosis research, 1990 - Elsevier
We developed the new system in which the platelet aggregation was detected turbidimetrically
using glass cuvettes which were coated cultured vascular endothelial cells. Using this …

Development and assessment of enzyme immunoassay for platelet-derived microparticles

…, S Saito, Y Nagamura, H Ito, Y Kimura… - Thrombosis and …, 2001 - thieme-connect.com
Platelet-derived microparticles (PMPs) are released from platelets through the platelet
activation by high shear stress, collagen, or calcium ionophore (A23187). PMPs are observed in …