In several neurodegenerative diseases that are collectively called tauopathies, progressive
accumulation of tau in the brain is closely associated with neurodegeneration and cognitive …

Purpose To provide an overview on positron emission tomography (PET) imaging of tau
pathology in Alzheimer’s disease (AD) and other neurodegenerative disorders. Results Different …

Tau deposition is one of the neuropathological hallmarks in Alzheimer’s disease as well as
in other neurodegenerative disorders called tauopathies. Recent efforts to develop selective …

Accumulation of intracellular tau fibrils has been the focus of research on the mechanisms
of neurodegeneration in Alzheimer's disease (AD) and related tauopathies. Here, we have …

While considerable effort has focused on developing positron emission tomography β-amyloid
imaging radiotracers for the early diagnosis of Alzheimer's disease, no radiotracer is …

Imaging of neurofibrillary pathology in the brain helps in diagnosing dementia, tracking
disease progression, and evaluating the therapeutic efficacy of antidementia drugs. The …

Neurofibrillary tangles in Alzheimer disease (AD) brains are composed of the microtubule-associated
protein tau. Noninvasive monitoring of tau protein aggregates in the living brain …

Non-invasive imaging of tau pathology in the living brain would be useful for accurately
diagnosing Alzheimer’s disease, tracking disease progression, and evaluating the treatment …

Extensive deposition of dense amyloid fibrils is a characteristic neuropathologic hallmark in
Alzheimer's disease (AD). Noninvasive detection of these molecules is potentially useful for …

Neurofibrillary tangles (NFTs), neuropil threads, and neuritic elements of senile plaques
predominantly comprise hyperphosphorylated tau protein and represent pathological …