Phase I study of α-galactosylceramide-pulsed antigen presenting cells administration to the nasal submucosa in unresectable or recurrent head and neck cancer
T Uchida, S Horiguchi, Y Tanaka, H Yamamoto… - Cancer Immunology …, 2008 - Springer
Background Human Vα24 natural killer T (NKT) cells are activated by the specific ligand, α-galactosylceramide
(α-GalCer), in a CD1d-dependent manner. Potent anti-tumor activity of …
(α-GalCer), in a CD1d-dependent manner. Potent anti-tumor activity of …
Catechin safely improved higher levels of fatness, blood pressure, and cholesterol in children
T Matsuyama, Y Tanaka, I Kamimaki, T Nagao… - …, 2008 - Wiley Online Library
Objective: The purpose of this study was to evaluate the effects of a catechin‐rich beverage
on body fat and cardiovascular disease risk factors in obese children and to verify the safety …
on body fat and cardiovascular disease risk factors in obese children and to verify the safety …
MR analysis of the substantia innominata in normal aging, Alzheimer disease, and other types of dementia
…, T Asano, H Sakurai, Y Tanaka… - American Journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The substantia innominata can be visualized on coronal
thin-section T2-weighted MR images. The purpose of this study was to investigate the …
thin-section T2-weighted MR images. The purpose of this study was to investigate the …
Acrolein induced both pulmonary inflammation and the death of lung epithelial cells
Acrolein, a compound found in cigarette smoke, is a major risk factor for respiratory diseases.
Previous research determined that both acrolein and cigarette smoke produced reactive …
Previous research determined that both acrolein and cigarette smoke produced reactive …
CCR 7 ligands are required for development of experimental autoimmune encephalomyelitis through generating IL-23-dependent Th17 cells
…, T Yasuda, K Aritomi, H Nakano, Y Tanaka… - The Journal of …, 2009 - journals.aai.org
CCL19 and CCL21 are thought to be critical for experimental autoimmune encephalomyelitis
(EAE) induction, but their precise role is unknown. We examined the role of these …
(EAE) induction, but their precise role is unknown. We examined the role of these …
SATB1 plays a critical role in establishment of immune tolerance
M Kondo, Y Tanaka, T Kuwabara, T Naito… - The Journal of …, 2016 - journals.aai.org
Special AT-rich sequence binding protein 1 (SATB1) is a genome organizer that is expressed
by T cells. T cell development is severely impaired in SATB1 null mice; however, because …
by T cells. T cell development is severely impaired in SATB1 null mice; however, because …
Predictors of a better outcome of pneumatic dilatation in patients with primary achalasia
Y Tanaka, K Iwakiri, N Kawami, H Sano… - Journal of …, 2010 - Springer
Objective Pneumatic dilatation (PD) has been widely used in the treatment of primary achalasia.
The aim of this study was to evaluate the effectiveness of PD and its predictive factors in …
The aim of this study was to evaluate the effectiveness of PD and its predictive factors in …
Antigen chemically coupled to the surface of liposomes are cross-presented to CD8+ T cells and induce potent antitumor immunity
…, H Ishida, K Kajino, K Ogasawara, Y Tanaka… - the Journal of …, 2006 - journals.aai.org
We have previously demonstrated that liposomes with differential lipid components display
differential adjuvant effects when Ags are chemically coupled to their surfaces. In the present …
differential adjuvant effects when Ags are chemically coupled to their surfaces. In the present …
The prokinetic effect of mosapride citrate combined with omeprazole therapy improves clinical symptoms and gastric emptying in PPI-resistant NERD patients with …
…, T Kawagoe, A Horie, M Shimpuku, Y Tanaka… - Journal of …, 2010 - Springer
Background Previous studies have shown that non-erosive reflux disease (NERD) patients
are less sensitive to proton pump inhibitor (PPI) treatment than patients with erosive reflux …
are less sensitive to proton pump inhibitor (PPI) treatment than patients with erosive reflux …
Transient lower esophageal sphincter relaxations (TLESRs) are the major mechanism of gastroesophageal reflux but are not the cause of reflux disease
K Iwakiri, Y Hayashi, M Kotoyori, Y Tanaka… - Digestive diseases and …, 2005 - Springer
In healthy subjects, the rate of acid reflux during transient lower esophageal sphincter
relaxations (TLESRs) is more frequent at the proximal margin of the LES. In this study, we …
relaxations (TLESRs) is more frequent at the proximal margin of the LES. In this study, we …