Vulnerable periods during the development of the nervous system are sensitive to
environmental insults because they are dependent on the temporal and regional emergence …

Cerebral palsy is the commonest physical disability in childhood, occurring in 2.0 to 2.5 per
1000 live births. Although the total number of children with cerebral palsy has remained …

Global hypoxic-ischemic injury (HII) to the brain is a significant cause of mortality and severe
neurologic disability. Imaging plays an important role in the diagnosis and treatment of HII …

OBJECTIVES. The objectives of this study were to delineate the etiologic profile and
neurodevelopmental outcome of neonatal seizures in the current era of neonatal intensive …

Cerebral hypoxia-ischemia (asphyxia) occurring in the fetus and newborn infant is a major
cause of acute mortality and chronic neurological disability in survivors. This review …

Imaging is pivotal in the evaluation and management of patients with seizure disorders.
Elegant structural neuroimaging with magnetic resonance imaging (MRI) may assist in …

Objective. The aim of this study was to establish whether abnormal signal intensity in the
posterior limb of the internal capsule (PLIC) on magnetic resonance imaging is an accurate …

• In the literature on neonatal encephalopathy, the pervasive assumption is that once infants
with major malformations or infections have been excluded, most of the remaining cases are …

Hypoxic-ischemic encephalopathy (HIE) is a major cause of neurological sequelae in (near-
) term newborns. Despite the use of therapeutic hypothermia, a significant number of …

Children born preterm and of very low birth weight have an increased incidence of learning
difficulties, but little is known about the specific nature of their cognitive deficits and the …