As systemic therapy of metastatic breast cancer improves, CNS involvement is becoming a
more widespread problem. This article summarizes the current knowledge regarding the …

Brain metastases are neoplasms that originate in tissues outside the brain and then spread
secondarily to the brain. Metastases to the brain are the most common intracranial tumours …

Background Correctly staging lung cancer is important because the treatment options and
prognosis differ significantly by stage. Several noninvasive imaging studies and invasive …

Context.—For the treatment of a single metastasis to the brain, surgical resection combined
with postoperative radiotherapy is more effective than treatment with radiotherapy alone …

Background Results from a previous phase 3 study suggested that prophylactic cranial
irradiation reduces the incidence of symptomatic brain metastases and prolongs overall …

BACKGROUND With the advent of new therapies for metastatic carcinoma to the brain,
patterns of intracranial disease and factors influencing survival become important …

A joint initiative by the British Thoracic Society and the Society for Cardiothoracic Surgery in
Great Britain and Ireland was undertaken to update the 2001 guidelines for the selection …

Introduction Accurate staging of lymph node involvement is a critical aspect of the initial
management of nonmetastatic non-small cell lung cancer (NSCLC). We sought to determine …

A recent meeting was held on March 22, 2019, among the FDA, clinical scientists,
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …

Background Correctly staging lung cancer is important because the treatment options and
the prognosis differ significantly by stage. Several noninvasive imaging studies including …