Purpose—The purpose of this statement is to review the literature on childhood stroke and to
provide recommendations for optimal diagnosis and treatment. This statement is intended …

Superparamagnetic iron oxide nanoparticles have diverse diagnostic and potential
therapeutic applications in the central nervous system (CNS). They are useful as magnetic …

Rapid MRI of the molecular diffusion of water demonstrated cerebral infarcts in 32 patients.
We studied these patients at various times following the onset of ischemic symptoms and …

Background and Purpose—To develop recommendations for the establishment of
comprehensive stroke centers capable of delivering the full spectrum of care to seriously ill …

Worldwide, stroke is a leading cause of death and disability. Recombinant tissue
plasminogen activator (rtPA) was approved a decade ago for the treatment of acute ischemic …

PURPOSE Our purpose was to evaluate the clinical efficacy, sensitivity, and specificity of
echo-planar diffusion-weighted MR imaging in patients with acute infarction. METHODS We …

In the investigation of ischemic stroke, conventional structural magnetic resonance (MR)
techniques (eg, T1-weighted imaging, T2-weighted imaging, and proton density-weighted …

Patients may present to the hospital at various times after an ischemic stroke. Many present
weeks after a neurologic deficit has occurred, as is often the case with elderly patients and …

Background and Purpose—Diffusion-weighted MRI (DWI) is highly sensitive in detecting
early cerebral ischemic changes in acute stroke patients. In this study we compared the …

Diffusion‐weighted magnetic resonance imaging detects ischemic injury within minutes after
onset, and has been used to demonstrate drug efficacy in animal models of stroke. In 50 …