Purpose of review Two large-scale controlled clinical trials have provided Class I evidence
for the benefit of deep brain stimulation (DBS) as a therapy for refractory epilepsy. However …

Hypothalamic hamartomas and gelastic seizures are often associated with cognitive
deterioration, behavioral problems, and poor response to anticonvulsant treatment or …

Episodic brain disorders (EBD) form an intriguing group of neurological diseases in which at
least some of the symptoms occur in attacks. The hypothalamus integrates many brain …

A previous magnetic resonance imaging study from our laboratory reported significant
temporal lobe volume deficits in cortical gray matter, white matter, and anterior hippocampus …

PURPOSE To investigate the clinical significance of MR-defined asymmetry of the fornix and
mamillary body for presurgical determination of the side of hippocampal sclerosis in patients …

Physiological evidence has shown that the anterior thalamus (AN) and its associated
efferents/afferents constitute an important propagation pathway for one animal model of …

PURPOSE To determine whether mamillary body atrophy is caused by deafferentation of the
mamillary body in patients with mesial temporal sclerosis. METHODS We studied 36 …

The major chemical generalized seizure model is pentylenetetrazol (PTZ), a compound that
provides similarities between human petit mal and grand mal seizures. Focal deep brain …

Hypothalamic hamartomas are rare malformations containing neurons that can be
associated with a remarkable epileptic syndrome. This syndrome is characterized by …