Pancreatic endocrine tumors (PETs) have long fascinated clini-cians, because some can
release biologically active hormones that cause distinct syndromes and provide important …

Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem neurocutaneous
syndrome characterized by the development of multiple hamartomas distributed throughout …

This review focuses on discussing the main modifications of the recently published 2017
WHO Classification of Neoplasms of the Neuroendocrine Pancreas (panNEN). Recent …

Purpose: In mice, genetic changes that inactivate the retinoblastoma tumor suppressor
pathway often result in pancreatic neuroendocrine tumors (Pan-NETs). Conversely, in …

Purpose Insulinomas are a rare type of neuroendocrine tumors, originating in the pancreas,
difficult to diagnose and to treat. Due to its rarity, insulinomas are a not well-known …

Abstract Approximately 5–10% of neuroendocrine tumors (NETs) of the
gastroenteropancreatic system (GEP) have a hereditary background. The known inherited …

Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem disorder
characterised by the development of multiple hamartomas in numerous organs. It is caused …

Larson AM, Hedgire SS, Deshpande V, Stemmer‐Rachamimov AO, Harisinghani MG,
Ferrone CR, Shah U, Thiele EA. Pancreatic neuroendocrine tumors in patients with tuberous …

The endocrine cells of the pancreas and their related cells throughout the gastrointestinal
tract give rise to a variety of tumors that pose a diagnostic challenge. There has been …

Insulinoma and glucagonoma are two rare functioning neoplasms of the neuroendocrine
cells of the pancreas, respectively, characterized by an uncontrolled over-secretion of insulin …