Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function

CK Willie, FL Colino, DM Bailey, YC Tzeng… - Journal of neuroscience …, 2011 - Elsevier
There is considerable utility in the use of transcranial Doppler ultrasound (TCD) to assess
cerebrovascular function. The brain is unique in its high energy and oxygen demand but …

Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: mechanisms of regulation, measurement, and interpretation

PN Ainslie, J Duffin - American Journal of Physiology …, 2009 - journals.physiology.org
Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

MRI measures of middle cerebral artery diameter in conscious humans during simulated orthostasis

JM Serrador, PA Picot, BK Rutt, JK Shoemaker… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—The relationship between middle cerebral artery (MCA) flow
velocity (CFV) and cerebral blood flow (CBF) is uncertain because of unknown vessel …

Cerebral blood flow velocity underestimates cerebral blood flow during modest hypercapnia and hypocapnia

NS Coverdale, JS Gati, O Opalevych… - Journal of applied …, 2014 - journals.physiology.org
To establish the accuracy of transcranial Doppler ultrasound (TCD) measures of middle
cerebral artery (MCA) cerebral blood flow velocity (CBFV) as a surrogate of cerebral blood …

[HTML][HTML] Cerebrovascular reactivity measurement using magnetic resonance imaging: a systematic review

E Sleight, MS Stringer, I Marshall, JM Wardlaw… - Frontiers in …, 2021 - frontiersin.org
Cerebrovascular reactivity (CVR) magnetic resonance imaging (MRI) probes cerebral
haemodynamic changes in response to a vasodilatory stimulus. CVR closely relates to the …

Elevation in cerebral blood flow velocity with aerobic fitness throughout healthy human ageing

PN Ainslie, JD Cotter, KP George… - The Journal of …, 2008 - Wiley Online Library
It is known that cerebral blood flow declines with age in sedentary adults, although previous
studies have involved small sample sizes, making the exact estimate of decline imprecise …

Assessment of middle cerebral artery diameter during hypocapnia and hypercapnia in humans using ultra-high-field MRI

J Verbree, ASGT Bronzwaer, E Ghariq… - Journal of applied …, 2014 - journals.physiology.org
In the evaluation of cerebrovascular CO2 reactivity measurements, it is often assumed that
the diameter of the large intracranial arteries insonated by transcranial Doppler remains …

Transcranial Doppler ultrasound: valid, invalid, or both?

PN Ainslie, RL Hoiland - Journal of Applied Physiology, 2014 - journals.physiology.org
DESPITE CONSIDERABLE ANATOMICAL knowledge acquired by anatomists three
centuries ago, little was known about the brain's circulatory control until the latter half of the …

Regulation of the cerebral circulation by arterial carbon dioxide

RL Hoiland, JA Fisher, PN Ainslie - Comprehensive physiology, 2011 - Wiley Online Library
Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

Cerebral artery dilatation maintains cerebral oxygenation at extreme altitude and in acute hypoxia—an ultrasound and MRI study

MH Wilson, MEG Edsell… - Journal of Cerebral …, 2011 - journals.sagepub.com
Transcranial Doppler is a widely used noninvasive technique for assessing cerebral artery
blood flow. All previous high altitude studies assessing cerebral blood flow (CBF) in the field …