White matter lesions, commonly seen on MRIs of elderly people, are related to various
geriatric disorders, including cerebrovascular diseases, cardiovascular diseases, dementia …

White matter hyperintensities (WMH) are commonly seen in the brain of healthy elderly
subjects and patients with several neurological and vascular disorders. A truly reliable and …

The extent and pattern of demyelination in the cerebral cortex was determined in 78 tissue
blocks from the brains of 20 multiple sclerosis (MS) patients and 28 tissue blocks from 7 …

RATIONALE AND OBJECTIVES: Brain lesions, especially white matter lesions (WMLs), are
associated with cardiac and vascular disease, but also with normal aging. Quantitative …

BACKGROUND AND PURPOSE: Quantification of MR can provide objective, accurate
criteria for evaluation of a given MR sequence. We quantitatively compared conventional …

The role of quantitative image analysis in large clinical trials is continuously increasing.
Several methods are available for performing white matter hyperintensity (WMH) volume …

Objective: To determine whether memory performance in hypertensive subjects induces
diminished parietal and prefrontal blood flow activation relative to normotensive subjects but …

Background Autopsy studies showed cortical and juxtacortical multiple sclerosis (MS)
plaques. Fluid-attenuated inversion recovery (FLAIR) is an advanced magnetic resonance …

Grey matter hypointensity on T2-weighted magnetic resonance imaging (MRI) scans,
suggesting iron deposition, has been described in multiple sclerosis (MS) and is related to …

OBJECTIVES: To examine the frequency of central nervous system (CNS) disease in
primary Sjögren's syndrome (pSS) and indicate ways in which cerebral magnetic resonance …