Glaucoma and the brain: trans-synaptic degeneration, structural change, and implications for neuroprotection

M Lawlor, H Danesh-Meyer, LA Levin… - Survey of …, 2018 - Elsevier
A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …

Why does the cortex reorganize after sensory loss?

AK Singh, F Phillips, LB Merabet, P Sinha - Trends in cognitive sciences, 2018 - cell.com
A growing body of evidence demonstrates that the brain can reorganize dramatically
following sensory loss. Although the existence of such neuroplastic crossmodal changes is …

Changes in cortical grey matter density associated with long-standing retinal visual field defects

CC Boucard, AT Hernowo, RP Maguire, NM Jansonius… - Brain, 2009 - academic.oup.com
Retinal lesions caused by eye diseases such as glaucoma and age-related macular
degeneration can, over time, eliminate stimulation of parts of the visual cortex. This could …

Thick visual cortex in the early blind

J Jiang, W Zhu, F Shi, Y Liu, J Li, W Qin… - Journal of …, 2009 - Soc Neuroscience
We investigated the key neurodevelopmental factors that determine cortical thickness,
namely synaptogenesis and regression, by analyzing the thickness of the visual cortex in …

Using magnetic resonance imaging to assess visual deficits: a review

HDH Brown, RL Woodall, RE Kitching… - Ophthalmic and …, 2016 - Wiley Online Library
Purpose Over the last two decades, magnetic resonance imaging (MRI) has been widely
used in neuroscience research to assess both structure and function in the brain in health …

Abnormal spontaneous brain activity in type 2 diabetic retinopathy revealed by amplitude of low-frequency fluctuations: a resting-state fMRI study

ZL Wang, L Zou, ZW Lu, XQ Xie, ZZ Jia, CJ Pan… - Clinical Radiology, 2017 - Elsevier
Aim To explore the altered spontaneous cerebral activity patterns and impaired functional
regions in patients with diabetic retinopathy (DR) using resting-state functional magnetic …

[HTML][HTML] White matter consequences of retinal receptor and ganglion cell damage

S Ogawa, H Takemura, H Horiguchi… - … & Visual Science, 2014 - jov.arvojournals.org
Purpose.: Patients with Leber hereditary optic neuropathy (LHON) and cone-rod dystrophy
(CRD) have central vision loss; but CRD damages the retinal photoreceptor layer, and …

Afferent visual pathways in multiple sclerosis: a review

SL Graham, A Klistorner - Clinical & experimental …, 2017 - Wiley Online Library
Multiple sclerosis (MS) is a disease of the central nervous system that involves inflammation
and demyelination at multiple sites and causes a wide variety of clinical presentations with …

Neuroplasticity in cerebral visual impairment (CVI): Assessing functional vision and the neurophysiological correlates of dorsal stream dysfunction

CR Bennett, CM Bauer, ES Bailin… - … & Biobehavioral Reviews, 2020 - Elsevier
Cerebral visual impairment (CVI) results from perinatal injury to visual processing structures
and pathways and is the most common individual cause of pediatric visual impairment and …

Morphometric analyses of the visual pathways in macular degeneration

AT Hernowo, D Prins, HA Baseler, T Plank, AD Gouws… - Cortex, 2014 - Elsevier
Introduction Macular degeneration (MD) causes central visual field loss. When field defects
occur in both eyes and overlap, parts of the visual pathways are no longer stimulated …