Proton magnetic resonance spectroscopy in brain tumours: clinical applications

IM Burtscher, S Holtås - Neuroradiology, 2001 - Springer
Parallel to the rapid development of clinical MRI, MR spectroscopy (MRS) has, after starting
as an analytical tool used in chemistry and physics, evolved to a noninvasive clinical …

Recent advances in the imaging of programmed cell death

FG Blankenberg - Current pharmaceutical design, 2004 - ingentaconnect.com
A deficiency or an excess of programmed cell death (apoptosis) is an integral component of
autoimmune disorders, organ and bone marrow transplant rejection, and cancer. A …

Proton MR spectroscopy in children with bipolar affective disorder: preliminary observations

M Castillo, L Kwock, H Courvoisie… - American Journal of …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Bipolar affective disorder (BPAD) can have its onset
during childhood, but the diagnosis may be difficult to establish on the basis of clinical …

3T 1H-MR spectroscopy in grading of cerebral gliomas: comparison of short and intermediate echo time sequences

J Kim, KH Chang, DG Na, IC Song… - American journal …, 2006 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Echo time (TE) can have a large influence on the spectra
in proton MR spectroscopy (1H-MR spectroscopy). The purpose of this study was to …

Serial proton MR spectroscopy of contrast-enhancing multiple sclerosis plaques: absolute metabolic values over 2 years during a clinical pharmacological study

I Mader, W Roser, L Kappos… - American journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The time courses of total creatine (Cr), N-acetylaspartate
(NAA), choline (Cho), and myo-inositol have not previously been investigated in the follow …

Fast high‐resolution prospective motion correction for single‐voxel spectroscopy

IM Adanyeguh, N Bikkamane Jayadev… - Magnetic …, 2024 - Wiley Online Library
Purpose To develop a fast high‐resolution image‐based motion correction method using
spiral navigators with multislice‐to‐volume registration. Methods A semi‐LASER sequence …

Reliable detection of macromolecules in single‐volume 1H NMR spectra of the human brain

U Seeger, I Mader, T Nägele, W Grodd… - … in Medicine: An …, 2001 - Wiley Online Library
In short echo time proton MR spectra of the brain, resonances from macromolecules are
visible. The macromolecular resonances in the 0.5–2.0 ppm region can be affected by lipid …

Proton magnetic resonance spectroscopy of brain-stem lesions

J Smith, A Londono, M Castillo, L Kwock - Neuroradiology, 2002 - Springer
The imaging findings of brain-stem lesions are often nonspecific and histological diagnosis
is limited because of fear of complications associated with biopsy. A noninvasive method for …

Proton MR spectroscopy in patients with acute temporal lobe seizures

M Castillo, JK Smith, L Kwock - American journal of …, 2001 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Decreases in N-acetyl aspartate (NAA) as seen by proton
MR spectroscopy are found in hippocampal sclerosis, and elevated levels of lipids/lactate …

Imaging cell death in vivo

F Blankenberg, C Mari… - The Quarterly Journal of …, 2003 - search.proquest.com
A technique to image programmed cell death would be useful both in clinical care and in
drug development. The most widely studied agent for the in vivo study of apoptosis is …