Magnetic resonance imaging assessment of tissue iron is becoming increasingly important
in the management of transfusional iron load because it is noninvasive, relatively widely …

Patients with transfusion-dependent anemia develop cardiac and endocrine toxicity from
iron overload. Classically, serum ferritin and liver biopsy have been used to monitor patient …

Over the last 20 years, management for thalassemia major has improved to the point where
we predict that patients' life expectancy will approach that of the normal population. These …

The endocrinological complications in β-thalassemia major patients do affect the life quality
to a large extend. In this study, the endocrinological complications of 47 β-thalassemia …

In thalassaemic patients, neurophysiological disturbances have been associated with high
serum ferritin levels and desferrioxamine therapy. In the presence of a magnetic field, ferritin …

The clinical utility of dual sequence (T1‐and T2‐weighted) magnetic resonance (MR)
imaging in estimating liver iron concentration (LIC) in 32 transfusion‐dependent β …

Hypogonadism, resulting from iron-induced pituitary dysfunction, is the most frequently
reported complication in patients with β-thalassaemia major. The aim of this study was to …

Aceruloplasminemia is a rare autosomal recessive disorder. The lack of ceruloplasmin
ferroxidase activity leads to parenchymal and reticuloendothelial iron overload, resulting in …

Over the last 20 years, the management of thalassemia major has improved to the point
where we predict that the patients' life expectancy will approach that of the normal …

OBJECTIVE. In transfusion-dependent β-thalassemia major, increased iron deposition in the
pituitary gland has a cytotoxic effect, leading mainly to hypogonadotropic hypogonadism …