Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Due to the heterogeneous nature of the disease, it is a challenge to capture disease activity
of multiple sclerosis (MS) in a reliable and valid way. Therefore, it can be difficult to assess …

Objectives: To quantify, using diffusion tensor imaging (DTI), the tissue damage in lesions
and normal-appearing white matter (NAWM) from a large cohort of patients with MS and to …

The term hepatic encephalopathy (HE) includes a spectrum of neuropsychiatric
abnormalities occurring in patients with liver dysfunction. Most cases are associated with …

Background Various types of pathologic mechanisms in multiple sclerosis (MS) can alter
magnetic resonance imaging (MRI) signals, and the appearance of remyelinated lesions on …

Neuro-axonal degeneration occurs progressively from the onset of multiple sclerosis and is
thought to be a significant cause of increasing clinical disability. Several histopathological …

Objective: To evaluate cognitive changes in a cohort of radiologically isolated syndromes
(RIS) suggestive of multiple sclerosis (MS) and to assess their relationship with quantitative …

Article abstract MRI is very sensitive in showing MS lesions throughout the CNS. Using MRI
for diagnostic purposes, however useful, is a complex issue because of limited specificity of …

Magnetic resonance (MR) imaging is very sensitive in showing disseminated MS lesions.
Subclinical MR progression occurs frequently, explaining why MR is now used to monitor …

Background: One of the diagnostic imaging hallmarks of MS is the uptake of IV administered
contrast material in new lesions in the brain, signaling blood–brain barrier breakdown and …