[HTML][HTML] Ligand design strategies to increase stability of gadolinium-based magnetic resonance imaging contrast agents

TJ Clough, L Jiang, KL Wong, NJ Long - Nature communications, 2019 - nature.com
Gadolinium (III) complexes have been widely utilised as magnetic resonance imaging (MRI)
contrast agents for decades. In recent years however, concerns have developed about their …

Gadolinium-based contrast agent accumulation and toxicity: an update

J Ramalho, RC Semelka, M Ramalho… - American Journal …, 2016 - Am Soc Neuroradiology
In current practice, gadolinium-based contrast agents have been considered safe when
used at clinically recommended doses in patients without severe renal insufficiency. The …

Safety of intrathecal administration of gadolinium-based contrast agents: a systematic review and meta-analysis

M Patel, A Atyani, JP Salameh, M McInnes… - Radiology, 2020 - pubs.rsna.org
Background The use of MR cisternography with intrathecal administration of gadolinium-
based contrast agents (GBCAs) is limited by a lack of understanding of the relationship …

Exposure to gadolinium and neurotoxicity: current status of preclinical and clinical studies

CA Mallio, À Rovira, PM Parizel, CC Quattrocchi - Neuroradiology, 2020 - Springer
Purpose Gadolinium is a rare-earth lanthanide metal that is known to have a direct
neurotoxic effect. The scope of the present review is to summarize the current preclinical and …

Multiorgan gadolinium (Gd) deposition and fibrosis in a patient with nephrogenic systemic fibrosis—an autopsy-based review

S Sanyal, P Marckmann, S Scherer… - Nephrology Dialysis …, 2011 - academic.oup.com
Background. Nephrogenic systemic fibrosis (NSF) is a systemic disorder of patients with
severe renal insufficiency who have received gadolinium (Gd)-based magnetic resonance …

The effect of perinatal gadolinium-based contrast agents on adult mice behavior

MA Khairinisa, Y Takatsuru, I Amano… - Investigative …, 2018 - journals.lww.com
Objectives The aim of this study was to examine the effects of perinatal exposure to
gadolinium (Gd)-based contrast agents (GBCAs) on the behavior of adulthood offspring …

Intrathecal gadolinium-enhanced MR cisternography: a comprehensive review

O Algin, B Turkbey - American Journal of Neuroradiology, 2013 - Am Soc Neuroradiology
CE-MRC has been in use for the past 15 years and was reported to be a useful method in
the evaluation of CSF disorders and hydrocephalus. The use of CE-MRC in conjunction with …

[HTML][HTML] Diagnosis and treatment of cerebrospinal fluid rhinorrhea following accidental traumatic anterior skull base fractures

M Ziu, JG Savage, DF Jimenez - Neurosurgical focus, 2012 - thejns.org
Cerebrospinal fluid rhinorrhea is a serious and potentially fatal condition because of an
increased risk of meningitis and brain abscess. Approximately 80% of all cases occur in …

Fatal gadolinium-induced encephalopathy following accidental intrathecal administration: a case report and a comprehensive evidence-based review

DA Provenzano, Z Pellis, L DeRiggi - Regional Anesthesia & Pain …, 2019 - rapm.bmj.com
Gadolinium-based contrast agents (GBCAs) have been suggested as off-label alternatives
to iodine-based contrast agents for fluoroscopic imaging during interventional pain …

Gadolinium released from MR contrast agents is deposited in brain tumors: in situ demonstration using scanning electron microscopy with energy dispersive X-ray …

D Xia, RL Davis, JA Crawford, JL Abraham - Acta Radiologica, 2010 - Taylor & Francis
Background: Gadolinium (Gd)-containing MRI contrast agents (GdCA) are widely used in
studies of brain tumors, and a number of reports suggest that under certain conditions, such …