Survival in people infected with HIV has improved because of an increasingly powerful array
of antiretroviral treatments, but neurological symptoms due to comorbid conditions, including …

Progressive multifocal leukoencephalopathy is caused by the JC polyomavirus (JCV) and is
one of the most feared complications of HIV-1 infection. Unlike other opportunistic infections …

We describe the clinical course of a patient with multiple sclerosis in whom progressive
multifocal leukoencephalopathy (PML), an opportunistic viral infection of the central nervous …

Nothing is more disappointing for patients than when a promising new treatment hits a
roadblock because of unexpected side effects. This is what happened when natalizumab …

Since its initial description, there have been significant changes in the epidemiology,
pathogenesis, and clinical and imaging manifestations of JCV infection of brain. The most …

Polyoma viruses are ubiquitous infecting many different mammalian species including
humans. There are five known human polyoma viruses. JC virus and BK virus are two …

Natalizumab is a new treatment option for patients with active relapsing-remitting multiple
sclerosis. In phase III studies, natalizumab was highly effective and well tolerated; however …

Progressive multifocal leukoencephalopathy (PML) is an uncommon and often fatal
demyelinating disease of human central nervous system, which is caused by reactivation of …

Focal neurological disease in patients with acquired immunodeficiency syndrome may be
caused by various opportunistic pathogens and malignancies, including Toxoplasma gondii …

Imaging plays an important role in the diagnosis and treatment of brain abscess, pyogenic
infection, and encephalitis. The role of CT and MRI in the diagnosis and management of …