Metals in neurobiology: probing their chemistry and biology with molecular imaging

EL Que, DW Domaille, CJ Chang - Chemical reviews, 2008 - ACS Publications
The brain is a singular organ of unique biological complexity that serves as the command
center for cognitive and motor function. As such, this specialized system also possesses a …

Imaging approaches to Parkinson disease

DJ Brooks - Journal of Nuclear Medicine, 2010 - Soc Nuclear Med
Parkinson disease (PD) is associated with nigral degeneration and striatal dopamine
deficiency. Demonstrating midbrain structural abnormalities with transcranial sonography or …

Deep neural networks for anatomical brain segmentation

A de Brebisson, G Montana - … of the IEEE conference on computer …, 2015 - cv-foundation.org
We present a novel approach to automatically segment magnetic resonance (MR) images of
the human brain into anatomical regions. Our methodology is based on a deep artificial …

[HTML][HTML] Predictive markers for Parkinson's disease using deep neural nets on neuromelanin sensitive MRI

S Shinde, S Prasad, Y Saboo, R Kaushick, J Saini… - NeuroImage: Clinical, 2019 - Elsevier
Neuromelanin sensitive magnetic resonance imaging (NMS-MRI) has been crucial in
identifying abnormalities in the substantia nigra pars compacta (SNc) in Parkinson's disease …

Volumetric segmentation of brain regions from MRI scans using 3D convolutional neural networks

F Ramzan, MUG Khan, S Iqbal, T Saba… - IEEE Access, 2020 - ieeexplore.ieee.org
Automated brain segmentation is an active research domain due to the association of
various neurological disorders with different regions of the brain, to help medical …

High resolution magnetic susceptibility mapping of the substantia nigra in Parkinson's disease

AK Lotfipour, S Wharton, ST Schwarz… - Journal of Magnetic …, 2012 - Wiley Online Library
Purpose: To determine if tissue magnetic susceptibility is a more direct marker of tissue iron
content than other MR markers of iron. This study presents the first quantitative, in vivo …

White matter involvement in idiopathic Parkinson disease: a diffusion tensor imaging study

G Gattellaro, L Minati, M Grisoli… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Diffusion tensor imaging (DTI) offers a unique window on
the connectivity changes, extending beyond the basal ganglia, which accompany the …

Changes in substantia nigra and locus coeruleus in patients with early-stage Parkinson's disease using neuromelanin-sensitive MR imaging

C Ohtsuka, M Sasaki, K Konno, M Koide, K Kato… - Neuroscience …, 2013 - Elsevier
Neuromelanin-sensitive magnetic resonance imaging is able to visualize changes
associated with neuronal loss in the substantia nigra pars compacta (SNc) and locus …

Seven‐Tesla magnetic resonance images of the substantia nigra in Parkinson disease

DH Kwon, JM Kim, SH Oh, HJ Jeong… - Annals of …, 2012 - Wiley Online Library
Objective: To investigate anatomical changes in the substantia nigra (SN) of Parkinson
disease (PD) patients with age‐matched controls by using ultra‐high field magnetic …

Convolutional neural networks for skull-stripping in brain MR imaging using silver standard masks

O Lucena, R Souza, L Rittner, R Frayne… - Artificial intelligence in …, 2019 - Elsevier
Manual annotation is considered to be the “gold standard” in medical imaging analysis.
However, medical imaging datasets that include expert manual segmentation are scarce as …