This paper reviews the current applications of diffusion‐weighted and diffusion tensor MRI in
diseases of the brain white matter. The contribution that diffusion‐weighted imaging has …

Diffusion tensor imaging (DTI) is an effective means of quantifying parameters of
demyelination and axonal loss. The application of DTI in Multiple Sclerosis (MS) has yielded …

Myelin loss and axonal damage are both observed in white matter injuries. Each may have
significant impact on the long-term disability of patients. Currently, there does not exist a …

Diffusion imaging is a quantitative, MR-based technique potentially useful for the study of
multiple sclerosis (MS), due to its increased pathologic specificity over conventional MRI and …

Magnetic resonance imaging (MRI) is often divided into structural MRI and functional MRI
(fMRI). The former is a widely used imaging technique in research as well as in clinical …

MR offers by far the most sensitive technique for detecting multiple sclerosis (MS) lesions
and has proved to be an important paraclinical tool for diagnosing MS and monitoring …

Neuroaxonal loss is a major substrate of irreversible disability in multiple sclerosis, however,
its cause is not understood. In multiple sclerosis there may be intracellular sodium …

Background: Slow-burning inflammation is putatively associated with lesion expansion and
leads to progressive loss of axons and disability worsening. Objective: To investigate the …

Recent studies indicate that functional connectivity using low‐frequency BOLD fluctuations
(LFBFs) is reduced between the bilateral primary sensorimotor regions in multiple sclerosis …

PURPOSE: To determine whether the normal-appearing white matter (NAWM) regions
surrounding and remote from multiple sclerosis (MS) plaques have abnormal diffusional …