Lesions of the cerebral white matter (WM) result in focal neurobehavioral syndromes,
neuropsychiatric phenomena, and dementia. The cerebral WM contains fiber pathways that …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders …

Background and purpose The splenium of the corpus callosum is the most posterior part of
the corpus callosum. Its embryological development, anatomy, vascularization, function …

Leukodystrophies usually affect children, but in the last several decades, many instances of
adult leukodystrophies have been reported in the medical literature. Because the clinical …

Resistance to chemotherapy continues to be a critical issue in the clinical therapy of triple‐
negative breast cancer (TNBC). Epithelial–mesenchymal transition (EMT) is thought to …

Leukodystrophies constitute a large and heterogeneous group of genetic diseases primarily
affecting the white matter of the central nervous system. Different disorders target different …

Krabbe disease usually presents as a severe leukodystrophy in early infancy and childhood.
From a series of 11 patients and 30 cases previously reported in the literature we describe …

The term leukodystrophy refers to a group of conditions that are inherited and involve the
progressive destruction or loss of previously acquired myelin. 1 The most commonly …

The majority of newborns screening positive for Krabbe disease have not exhibited the
expected early infantile phenotype, with most clinically normal despite low …

BACKGROUND AND PURPOSE: In recent years, the discovery that mutations in the glial
fibrillary acidic protein gene (GFAP) were responsible for Alexander disease (AD) brought …