Deciphering the secret of successful aging depends on understanding the patterns and
biological underpinnings of cognitive and behavioral changes throughout adulthood. That …

We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

Myelin loss and axonal damage are both observed in white matter injuries. Each may have
significant impact on the long-term disability of patients. Currently, there does not exist a …

Both axon and myelin degeneration have significant impact on the long-term disability of
patients with white matter disorder. However, the clinical manifestations of the neurological …

Myelin damage, as seen in multiple sclerosis (MS) and other demyelinating diseases,
impairs axonal conduction and can also be associated with axonal degeneration. Accurate …

Cerebral white matter (WM) undergoes various degenerative changes with normal aging,
including decreases in myelin density and alterations in myelin structure. We acquired …

Creating a healthy, social classroom environment. This book explains how the brain, as a
social organism, learns best throughout the lifespan, from our early schooling through late …

In this article, the underlying theory of clinical diffusion MR imaging, including diffusion
tensor imaging (DTI) and fiber tractography, is reviewed. First, a brief explanation of the …

Magnetic resonance diffusion tensor imaging (DTI) is a non-invasive in vivo method for
characterizing the integrity of anatomical connections and white matter circuitry and provides …

White matter microstructural integrity was assessed using diffusion tensor imaging (DTI) in
25 young adults, 25 nondemented older adults, and 25 age-matched older adults with …