Pilocytic astrocytoma is the most common pediatric central nervous system glial neoplasm
and the most common pediatric cerebellar tumor. This tumor has a noteworthy benign …

Childhood, adolescent, and young adult (CAYA) cancer survivors treated with platinum-
based drugs, head or brain radiotherapy, or both have an increased risk of ototoxicity …

✓ Optic pathway gliomas represent approximately 3–5% of childhood intracranial tumors.
They usually occur in children during the first decade of life and are seen in 11–30% of …

Background Carboplatin plays an important role in the conservative management of
retinoblastoma, but is associated with risk of ototoxicity in these young children whose …

Background: The role of surgery in the management of gadolinium-enhancing pediatric
brainstem lesions on magnetic resonance imaging (MRI) has been a matter of open debate …

The prognosis and treatment outcome for primary brain tumors have remained unchanged
despite advances in anticancer drug discovery and development. In clinical trials, the …

Intra-arterial drug delivery circumvents the first-pass effect and is believed to increase both
efficacy and tolerability of primary and metastatic brain tumor therapy. The aim of this update …

Entry of human immunodeficiency virus type 1 (HIV-1) into cells is mediated by the virion
surface envelope (Env) glycoproteins, making it a desirable target for antiretroviral entry …

Simple Summary In the current study, we systematically reviewed the literature regarding the
management of optic pathway glioma (OPG). This review will analyze demographics …

Optic pathway–hypothalamic gliomas (OPHGs) are rare, often unresectable tumors that
mostly occur in childhood. Their biological behavior is unpredictable, although they tend to …