Background and Purpose—Numerous imaging techniques have been developed and
applied to evaluate brain hemodynamics. Among these are positron emission tomography …

In contrast to almost all other brain tumors, diffuse gliomas infiltrate extensively in the
neuropil. This growth pattern is a major factor in therapeutic failure. Diffuse infiltrative glioma …

BACKGROUND AND PURPOSE: Relative cerebral blood volume (rCBV) estimates for high-
grade gliomas computed with dynamic susceptibility contrast MR imaging are artificially …

The role of neuroimaging in patients with brain tumors is no longer simply to evaluate
structural abnormality and identify tumor-related complications. By transitioning from a …

Over the last few decades there has been considerable research into quantifying the
cerebral microvasculature with imaging, for use in studies of the human brain and various …

This article reviews the application of dynamic contrast-enhanced magnetic resonance
imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis …

Histopathologic evaluation of glioblastoma multiforme (GBM) at initial diagnosis is typically
performed on tissue obtained from regions of contrast enhancement (CE) as depicted on …

OBJECTIVE: Common contrast-enhancing malignant tumors of the brain are glioblastoma
multiforme (GBMs), anaplastic astrocytomas (AAs), metastases, and lymphomas, all of which …

Abstract Learning Objectives After completing this course, the reader will be able to:
Understand the rationale and validity of using MR perfusion techniques for selecting the …

Most tumours, even those of the same histological type and grade, demonstrate
considerable biological heterogeneity. Variations in genomic subtype, growth factor …