Although laughter and humour have been constituents of humanity for thousands if not
millions of years, their systematic study has begun only recently. Investigations into their …

The most common, and usually the only, endocrine disturbance in patients with
hypothalamic hamartoma (HH) and epilepsy is central precocious puberty (CPP). The …

The burst of laughter that is evoked by tickling is a primitive form of vocalization. It evolves
during an early phase of postnatal life and appears to be independent of higher cortical …

Hypothalamic hamartomas are uncommon but well-recognized developmental
malformations that are classically associated with gelastic seizures and other refractory …

The incidence of hypothalamic hamartomas (HHs) has increased since the introduction of
magnetic resonance (MR) imaging. The etiology of this anomaly and the pathogenesis of its …

Purpose Guidelines on pituitary incidentalomas evaluation and management are limited to
adults since there are no data on this matter in the paediatric population. We aim to analyse …

Purpose To highlight the role of in vivo magnetic resonance spectroscopy (MRS) as a non-
invasive tool that can clarify the etiology of sellar tumors by presenting the case of a boy with …

BACKGROUND AND PURPOSE: There is variability in the literature concerning the
appearance and histology of hypothalamic hamartomas. This study correlates the MR …

Purpose: Hypothalamic hamartomas (HHs) have been associated with uncontrolled
seizures, and aggressive therapy including surgery is often recommended. However, some …

Hypothalamic hamartomas (HH) are rare, non-neoplastic heterotopic tissues which contains
normal neurons and glia including oligodendrocytes and fibrillary astrocytes but in an …