Does perinatal asphyxia impair cognitive function without cerebral palsy?

FF Gonzalez, SP Miller - Archives of Disease in Childhood-Fetal and …, 2006 - fn.bmj.com
Some studies on neurodevelopmental outcomes after neonatal encephalopathy have
suggested that cognitive deficits do not occur in the absence of cerebral palsy. It is …

[HTML][HTML] Aging, Neurodegenerative Disorders, and Cerebellum

IY Iskusnykh, AA Zakharova, ED Kryl'skii… - International Journal of …, 2024 - mdpi.com
An important part of the central nervous system (CNS), the cerebellum is involved in motor
control, learning, reflex adaptation, and cognition. Diminished cerebellar function results in …

Impaired trophic interactions between the cerebellum and the cerebrum among preterm infants

C Limperopoulos, JS Soul, H Haidar, PS Huppi… - …, 2005 - publications.aap.org
Background. Advanced neuroimaging techniques have brought increasing recognition of
cerebellar injury among premature infants. The developmental relationship between early …

[HTML][HTML] MicroRNA-210 suppresses junction proteins and disrupts blood-brain barrier integrity in neonatal rat hypoxic-ischemic brain injury

Q Ma, C Dasgupta, Y Li, L Huang, L Zhang - International journal of …, 2017 - mdpi.com
Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of
the serious complications associated with brain injury in neonatal hypoxic-ischemic …

Multimodal image analysis of clinical influences on preterm brain development

G Ball, P Aljabar, P Nongena, N Kennea… - Annals of …, 2017 - Wiley Online Library
Objective Premature birth is associated with numerous complex abnormalities of white and
gray matter and a high incidence of long‐term neurocognitive impairment. An integrated …

[HTML][HTML] White matter injury in term newborns with neonatal encephalopathy

AM Li, V Chau, KJ Poskitt, MA Sargent, BA Lupton… - Pediatric …, 2009 - nature.com
White matter injury (WMI) is the characteristic pattern of brain injury detected on magnetic
resonance imaging in the premature newborn. Focal noncystic WMI is increasingly …

[HTML][HTML] Additional value of 3-month cranial magnetic resonance imaging in infants with neonatal encephalopathy following perinatal asphyxia

CEJ Parmentier, MH Lequin, T Alderliesten… - The Journal of …, 2023 - Elsevier
Objective To assess the evolution of neonatal brain injury noted on magnetic resonance
imaging (MRI), develop a score to assess brain injury on 3-month MRI, and determine the …

Differential diagnosis of cerebellar atrophy in childhood

A Poretti, NI Wolf, E Boltshauser - European Journal of Paediatric …, 2008 - Elsevier
Starting from the imaging appearance of cerebellar atrophy (CA) we provide checklists for
various groups of CA: hereditary CA, postnatally acquired CA, and unilateral CA. We also …

Diffusion tensor imaging detects occult cerebellar injury in severe neonatal hypoxic-ischemic encephalopathy

ME Lemmon, MW Wagner, T Bosemani… - Developmental …, 2017 - karger.com
Background: Despite the benefits of whole-body hypothermia therapy, many infants with
hypoxic-ischemic encephalopathy (HIE) die or have significant long-term …

[HTML][HTML] PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic–Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling

S Zur Nedden, MS Safari, F Fresser, K Faserl… - Biomolecules, 2023 - mdpi.com
We recently identified protein kinase N1 (PKN1) as a negative gatekeeper of neuronal AKT
protein kinase activity during postnatal cerebellar development. The developing cerebellum …