It is surprising that the piriform cortex, when compared to the hippocampus, has been given
relatively little significance in human epilepsy. Like the hippocampus, it has a …

Epilepsy is a common neurologic disorder that manifests in diverse ways. There are
numerous seizure types and numerous mechanisms by which the brain generates seizures …

The central processing pathways of the human olfactory system are not fully understood.
The olfactory bulb projects directly to a number of cortical brain structures, but the distinct …

Importance A functional area associated with the piriform cortex, termedarea tempestas, has
been implicated in animal studies as having a crucial role in modulating seizures, but similar …

During mammalian evolution, primate neocortex expanded, shifting hippocampal functional
networks away from primary sensory cortices, towards association cortices. Reflecting this …

Objective In patients with epilepsy, seizure relapse and behavioral impairments can be
observed despite the absence of interictal epileptiform discharges (IED s). Therefore, the …

The piriform cortex (PC) is located at the junction of the temporal and frontal lobes. It is
involved physiologically in olfaction as well as memory and plays an important role in …

While recent studies suggest an important role of higher order olfactory brain areas for basic
olfactory performance, the extent to which cortical and peripheral neural markers account for …

Three subregions of the amygdala receive monosynaptic projections from the olfactory bulb,
making them part of primary olfactory cortex. These primary olfactory areas are located at the …

Olfactory dysfunction is manifested in a wide range of neurological and psychiatric diseases,
and often emerges prior to the onset of more classical symptoms and signs. From a …