Worldwide, stroke is a leading cause of death and disability. Recombinant tissue
plasminogen activator (rtPA) was approved a decade ago for the treatment of acute ischemic …

Objective: Cerebral perfusion imaging with computed tomography (CT) or magnetic
resonance (MR) is widely available. The optimum perfusion values to identify tissue at risk of …

Purpose To examine the variability in the qualitative and quantitative results of computed
tomographic (CT) perfusion imaging generated from identical source data of stroke patients …

Background and Purpose—We investigated whether computed tomography (CT) perfusion–
derived cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to …

Background and Purpose—Pretreatment infarct volume appears to predict clinical outcome
after intra-arterial therapy. To confirm the importance of infarct size in patients undergoing …

Purpose To quantify amide protein transfer (APT) effects in acidic ischemic lesions and
assess the spatial‐temporal relationship among diffusion, perfusion, and pH deficits in acute …

Amide proton transfer (APT) imaging, a variant of chemical exchange saturation transfer
MRI, has shown promise in detecting ischemic tissue acidosis following impaired aerobic …

Standard imaging in acute stroke is undertaken with the aim of diagnosing the underlying
cause and excluding stroke mimics. In the presence of ischaemic stroke, imaging is also …

In the past 5 years, the success of multiple randomized controlled trials of recanalization
therapy with endovascular thrombectomy has transformed the treatment of acute ischemic …

BACKGROUND AND PURPOSE: Various CTP parameters have been used to identify
ischemic penumbra. The purpose of this study was to determine the optimal CTP parameter …