Imaging biomarkers in multiple sclerosis

M Filippi, F Agosta - … Resonance Imaging: An Official Journal of …, 2010 - Wiley Online Library
Recent years have witnessed impressive advances in the use of magnetic resonance
imaging (MRI) for the assessment of patients with multiple sclerosis (MS). Complementary to …

MRI evidence for multiple sclerosis as a diffuse disease of the central nervous system

M Filippi, MA Rocca - Journal of neurology, 2005 - Springer
The classical view of MS as a chronic inflammatory demyelinating disease leading to the
formation of focal central nervous system (CNS) white matter (WM) lesions has been …

B cells from patients with multiple sclerosis induce cell death via apoptosis in neurons in vitro

RP Lisak, L Nedelkoska, JA Benjamins… - Journal of …, 2017 - Elsevier
B cells mediate multiple sclerosis (MS) pathogenesis by mechanisms unrelated to
immunoglobulin (Ig). We reported that supernatants (Sup) from cultured B cells from blood of …

Functional and structural connectivity of the motor network in pediatric and adult-onset relapsing-remitting multiple sclerosis

MA Rocca, M Absinta, L Moiola, A Ghezzi, B Colombo… - Radiology, 2010 - pubs.rsna.org
Purpose To elucidate the factors associated with the preservation of function in relapsing-
remitting (RR) multiple sclerosis (MS) by investigating effective connectivity changes of the …

Is a preserved functional reserve a mechanism limiting clinical impairment in pediatric MS patients?

MA Rocca, M Absinta, A Ghezzi, L Moiola… - Human brain …, 2009 - Wiley Online Library
We evaluated the functional magnetic resonance imaging (fMRI) correlates of simple
movement performance in patients with pediatric multiple sclerosis (MS) and their relation …

EFNS guidelines on the use of neuroimaging in the management of multiple sclerosis

M Filippi, MA Rocca, DL Arnold… - European journal of …, 2006 - Wiley Online Library
Magnetic resonance (MR)‐based techniques are widely used for the assessment of patients
with suspected and definite multiple sclerosis (MS). However, despite the publication of …

Functional magnetic resonance imaging correlates of cognitive performance in patients with a clinically isolated syndrome suggestive of multiple sclerosis at …

C Forn, MA Rocca, P Valsasina, I Boscá… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Background/Objective: To assess whether abnormalities on functional magnetic resonance
imaging (fMRI) are related to cognitive function in patients at presentation with clinically …

Advanced structural and functional brain MRI in multiple sclerosis

A Giorgio, N De Stefano - Seminars in neurology, 2016 - thieme-connect.com
Conventional magnetic resonance imaging (MRI) of the central nervous system is crucial for
an early and reliable diagnosis and monitoring of patients with multiple sclerosis (MS). Focal …

Future MRI tools in multiple sclerosis

M Filippi, M Absinta, MA Rocca - Journal of the neurological sciences, 2013 - Elsevier
Magnetic resonance imaging (MRI) is extremely sensitive in detecting multiple sclerosis
(MS)-related abnormalities. As a consequence, it has become an established tool to …

Early prognosis of multiple sclerosis

J Swanton, K Fernando, D Miller - Handbook of clinical neurology, 2014 - Elsevier
Establishing the prognosis for multiple sclerosis (MS) early in the disease course is critically
important for patients who develop this disease. Potentially, this information could be used to …