Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

The central nervous system, one of the most delicate microenvironments of the body, is
protected by the blood-brain barrier (BBB) regulating its homeostasis. BBB is a highly …

Superparamagnetic iron oxide nanoparticles have received great attention due to their
applications as contrast agents for magnetic resonance imaging (MRI). This feature article …

CNS lymphoma consists of 2 major subtypes: secondary CNS involvement by systemic
lymphoma and PCNSL. Contrast-enhanced MR imaging is the method of choice for …

Superparamagnetic iron oxide nanoparticles have diverse diagnostic and potential
therapeutic applications in the central nervous system (CNS). They are useful as magnetic …

Blood–brain barrier (BBB) together with enzymes restricts the entry of substances for
maintaining the internal milieu of the brain. Because of the presence of multiple endogenous …

Nanomedicine, the integration of nanotechnological tools in medicine demonstrated
promising potential to revolutionize the diagnosis and treatment of various human health …

The application of nanotechnology to medicine, commonly referred to as 'nanomedicine',
has the potential to transform our approach to human health and disease. Research at the …

Gadolinium (Gd) based contrast agents (GBCAs) in magnetic resonance imaging (MRI) are
used in daily clinical practice and appear safe in most patients; however, nephrogenic …

Central nervous system (CNS) diseases represent the largest and fastest-growing area of
unmet medical need. Nanotechnology plays a unique instrumental role in the revolutionary …