Methodological consensus on clinical proton MRS of the brain: Review and recommendations

M Wilson, O Andronesi, PB Barker… - Magnetic resonance …, 2019 - Wiley Online Library
Proton MRS (1H MRS) provides noninvasive, quantitative metabolite profiles of tissue and
has been shown to aid the clinical management of several brain diseases. Although most …

Clinical proton MR spectroscopy in central nervous system disorders

G Öz, JR Alger, PB Barker, R Bartha, A Bizzi, C Boesch… - Radiology, 2014 - pubs.rsna.org
A large body of published work shows that proton (hydrogen 1 [1H]) magnetic resonance
(MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality …

Advanced single voxel 1H magnetic resonance spectroscopy techniques in humans: Experts' consensus recommendations

G Öz, DK Deelchand, JP Wijnen, V Mlynárik… - NMR in …, 2021 - Wiley Online Library
Conventional proton MRS has been successfully utilized to noninvasively assess tissue
biochemistry in conditions that result in large changes in metabolite levels. For more …

[HTML][HTML] Magnetic resonance spectroscopy—revisiting the biochemical and molecular milieu of brain tumors

A Verma, I Kumar, N Verma, P Aggarwal, R Ojha - BBA clinical, 2016 - Elsevier
Background Magnetic resonance spectroscopy (MRS) is an established tool for in-vivo
evaluation of the biochemical basis of human diseases. On one hand, such lucid depiction …

Neuroimaging of mitochondrial disease

RP Saneto, SD Friedman, DWW Shaw - Mitochondrion, 2008 - Elsevier
Mitochondrial disease represents a heterogeneous group of genetic disorders that require a
variety of diagnostic tests for proper determination. Neuroimaging may play a significant role …

Spatial effects in the detection of γ‐aminobutyric acid: Improved sensitivity at high fields using inner volume saturation

RAE Edden, PB Barker - … in Medicine: An Official Journal of the …, 2007 - Wiley Online Library
Abstract The MEGA‐PRESS‐IVS method has been developed, which combines MEGA (a
frequency‐selective editing technique) editing with the point‐resolved spectroscopy …

Quantitative dynamic oxygen 17 MRI at 7.0 T for the cerebral oxygen metabolism in glioma

D Paech, AM Nagel, MN Schultheiss, R Umathum… - Radiology, 2020 - pubs.rsna.org
Background Altered metabolism is a characteristic of cancer. Because of a shift in glucose
metabolism from oxidative phosphorylation to lactate production for energy generation …

[HTML][HTML] Assessing metabolism and injury in acute human traumatic brain injury with magnetic resonance spectroscopy: current and future applications

MG Stovell, JL Yan, A Sleigh, MO Mada… - Frontiers in …, 2017 - frontiersin.org
Traumatic brain injury (TBI) triggers a series of complex pathophysiological processes.
These include abnormalities in brain energy metabolism; consequent to reduced tissue pO 2 …

Abnormal changes of synaptic excitability in migraine with aura

M Siniatchkin, M Sendacki, F Moeller, S Wolff… - Cerebral …, 2012 - academic.oup.com
Migraine patients are characterized by altered cortical excitability and information
processing between attacks. The relationship between these abnormalities is still poorly …

[HTML][HTML] MR image changes of normal-appearing brain tissue after radiotherapy

K Witzmann, F Raschke, EGC Troost - Cancers, 2021 - mdpi.com
Simple Summary Radiotherapy is one of the most important treatment options against
cancer. Irradiation of cancerous tissue either directly destroys the cancer cells or damages …