Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy

CF Rose, P Amodio, JS Bajaj, RK Dhiman… - Journal of …, 2020 - Elsevier
Hepatic encephalopathy (HE) is a frequent and serious complication of both chronic liver
disease and acute liver failure. HE manifests as a wide spectrum of neuropsychiatric …

[HTML][HTML] Alcohol's effects on the brain: neuroimaging results in humans and animal models

NM Zahr, A Pfefferbaum - Alcohol research: current reviews, 2017 - ncbi.nlm.nih.gov
Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Pathogenetic mechanisms of hepatic encephalopathy

D Häussinger, F Schliess - Gut, 2008 - search.proquest.com
Pathogenetic mechanisms of hepatic encephalopathy Page 1 Pathogenetic mechanisms of
hepatic encephalopathy D Häussinger, F Schliess c Competing interests: Declared. The …

MR imaging findings in hepatic encephalopathy

A Rovira, J Alonso, J Córdoba - American Journal of …, 2008 - Am Soc Neuroradiology
The term hepatic encephalopathy (HE) includes a spectrum of neuropsychiatric
abnormalities occurring in patients with liver dysfunction. Most cases are associated with …

[HTML][HTML] Astrocyte glutamine synthetase: importance in hyperammonemic syndromes and potential target for therapy

SW Brusilow, RC Koehler, RJ Traystman, AJL Cooper - Neurotherapeutics, 2010 - Elsevier
Many theories have been advanced to explain the encephalopathy associated with chronic
liver disease and with the less common acute form. A major factor contributing to hepatic …

Neuropsychological assessment of hepatic encephalopathy: ISHEN practice guidelines

C Randolph, R Hilsabeck, A Kato… - Liver …, 2009 - Wiley Online Library
Low‐grade or minimal hepatic encephalopathy (MHE) is characterised by relatively mild
neurocognitive impairments, and occurs in a substantial percentage of patients with liver …

Neuroimaging in alcohol use disorder: From mouse to man

M Fritz, AM Klawonn, NM Zahr - Journal of neuroscience …, 2022 - Wiley Online Library
This article provides an overview of recent advances in understanding the effects of alcohol
use disorders (AUD) on the brain from the perspective of magnetic resonance imaging (MRI) …

Hypoosmotic swelling and ammonia increase oxidative stress by NADPH oxidase in cultured astrocytes and vital brain slices

R Reinehr, B Görg, S Becker, N Qvartskhava… - Glia, 2007 - Wiley Online Library
The role of NADPH oxidase (NOX) and the regulatory subunit p47phox for hypoosmotic
ROS generation was studied in cultured rat astrocytes and brain slices of wilde type and …

Acute toxic leukoencephalopathy: potential for reversibility clinically and on MRI with diffusion-weighted and FLAIR imaging

AM McKinney, SA Kieffer, RT Paylor… - American Journal of …, 2009 - Am Roentgen Ray Soc
OBJECTIVE. Toxic leukoencephalopathy may present acutely or subacutely with
symmetrically reduced diffusion in the periventricular and supraventricular white matter …

Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction

SC Licata, PF Renshaw - Annals of the New York Academy of …, 2010 - Wiley Online Library
Proton magnetic resonance spectroscopy (1H MRS) is a noninvasive imaging technique that
permits measurement of particular compounds or metabolites within the tissue of interest. In …