Normal aging is associated with diminished brain perfusion measured as cerebral blood
flow (CBF), but previously it is difficult to accurately measure various aspects of perfusion …

The two most common forms of dementia are Alzheimer's disease (AD) followed by vascular
dementia (VaD), together accounting for a whopping 60-80% of total dementia cases …

Histological and magnetic resonance imaging studies have demonstrated that age-
associated alterations of the human brain may be at least partially related to vascular …

Vascular dementia is, in its current conceptual form, a distinct type of dementia with a
spectrum of specific clinical and pathophysiological features. However, in a very large …

We investigated the relationships between cerebral blood flow (CBF), cognitive, and mobility
decline in type 2 diabetes mellitus (T2DM) over a 2-year period. Seventy-three participants …

This work proposes a novel MRI method–Intrinsic Diffusivity Encoding of Arterial Labeled
Spin (IDEALS)–for the whole-brain mapping of water permeability in the human brain …

The purpose of this study was to evaluate the mechanisms of age‐related decline of
dopamine transporter (DAT) and dopamine D2‐like receptor (D2R) densities in the human …

Objective: We aimed to investigate sex-dependent alterations in resting-state relative
cerebral blood flow, amplitude of low-frequency fluctuations and relative cerebral blood flow …

This study was aimed to evaluate and compare the effect of chronic hypoxia and aging in the
oxidative status of brain vessels and synaptosomes. For this purpose we isolated brain …

Background: Pure autonomic failure (PAF) is a selective peripheral disorder in which Lewy
bodies form within the autonomic ganglia. Patients with this disorder usually have no central …