Background The spinocerebellar ataxias (SCAs) are a group of autosomal dominant
degenerative diseases characterized by cerebellar ataxia. Classified according to gene …

Polyglutamine diseases are hereditary neurodegenerative disorders caused by an
abnormal expansion of a trinucleotide CAG repeat, which encodes a polyglutamine tract. To …

PURPOSE:: This study accessed the feasibility of using tractography-based analysis to
evaluate the apparent diffusion coefficient (ADC) and fractional anisotropy (FA) of three …

Diffusion tensor imaging (DTI) histogram metrics are correlated with clinical parameters in
cerebral small vessel diseases (cSVD). Whether ADC histogram parameters derived from …

We describe the cases of 2 patients, a father and his son, with DRPLA who underwent MR
examinations prior to death and in whom postmortem examinations of the brain were …

Mild cognitive impairment and Alzheimer's dementia involve a grey matter disease,
quantifiable by 18 F-Fluorodeoxyglucose positron emission tomography (FDG-PET), but …

Dentatorubral-pallidoluysian atrophy (DRPLA) is an autosomal dominant
neurodegenerative disease clinically characterized by the presence of cerebellar ataxia in …

Purpose To investigate morphological changes of the superior and middle cerebellar
peduncles (SCP, MCP) in spinocerebellar degeneration (SCD) by observing “cerebellar …

Cerebral small vessel disease (cSVD) is a spectrum of clinical and imaging abnormalities
linked to the pathology of small penetrating arteries and arterioles in the brain irrigating …

While there are huge number of reports in the gray matter changes in Alzheimer's disease
(AD), there are also increasing number of reports on white matter changes in the cases of …