[HTML][HTML] Quantifying the metabolic signature of multiple sclerosis by in vivo proton magnetic resonance spectroscopy: current challenges and future outlook in the …

KM Swanberg, K Landheer, D Pitt, C Juchem - Frontiers in Neurology, 2019 - frontiersin.org
Proton magnetic resonance spectroscopy (1 H-MRS) offers a growing variety of methods for
querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …

Whole-brain N-acetylaspartate as a surrogate marker of neuronal damage in diffuse neurologic disorders

DJ Rigotti, M Inglese, O Gonen - American Journal of …, 2007 - Am Soc Neuroradiology
Proton MR spectroscopy (1H-MR spectroscopy) is a quantitative MR imaging technique
often used to complement the sensitivity of conventional MR imaging with specific metabolic …

[HTML][HTML] MRI in multiple sclerosis: what's inside the toolbox?

M Neema, J Stankiewicz, A Arora, ZD Guss, R Bakshi - Neurotherapeutics, 2007 - Elsevier
Magnetic resonance imaging (MRI) has played a central role in the diagnosis and
management of multiple sclerosis (MS). In addition, MRI metrics have become key …

Robust reconstruction of MRSI data using a sparse spectral model and high resolution MRI priors

R Eslami, M Jacob - IEEE transactions on medical imaging, 2010 - ieeexplore.ieee.org
We introduce a novel algorithm to address the challenges in magnetic resonance (MR)
spectroscopic imaging. In contrast to classical sequential data processing schemes, the …

Compartmentalized low‐rank recovery for high‐resolution lipid unsuppressed MRSI

I Bhattacharya, M Jacob - Magnetic resonance in medicine, 2017 - Wiley Online Library
Purpose To introduce a novel algorithm for the recovery of high‐resolution magnetic
resonance spectroscopic imaging (MRSI) data with minimal lipid leakage artifacts, from dual …

Spectral quantification for high-resolution MR spectroscopic imaging with spatiospectral constraints

Q Ning, C Ma, F Lam, ZP Liang - IEEE Transactions on …, 2016 - ieeexplore.ieee.org
Objective: To obtain reliable spectral estimation from magnetic resonance spectroscopic
imaging (MRSI) data. Methods: The proposed method takes advantage of prior knowledge …

Global N-acetylaspartate declines even in benign multiple sclerosis

DJ Rigotti, O Gonen, RI Grossman… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Neuro-axonal damage is a well known sequelae of MS
pathogeneses. Consequently, our aim was to test whether the∼ 20% of patients with MS …

[HTML][HTML] Reproducibility over a 1-month period of 1H-MR spectroscopic imaging NAA/Cr ratios in clinically stable multiple sclerosis patients

JP Mostert, Y Blaauw, MW Koch, AJ Kuiper… - European …, 2008 - Springer
Abstract N-acetylaspartate/creatine (NAA/Cr) ratios, assessed with proton magnetic
resonance spectroscopy, are increasingly used as a surrogate marker for axonal dysfunction …

A sparse reconstruction algorithm for parallel spiral MR spectroscopic imaging

R Eslami, M Jacob - … on Biomedical Imaging: From Nano to …, 2011 - ieeexplore.ieee.org
In this paper we propose an efficient sparse reconstruction scheme for the parallel MRSI
data acquired using a fast spiral scheme. We model the system using the MR priors …

[PDF][PDF] Exploiting Known Resonance Structure of Lipids for Improved Nuisance Removal from H-MRSI Data

Q Ning, F Lam, C Ma, B Clifford, ZP Liang - qiangning.info
Purpose: To exploit the known resonance structures of lipid (and water) signals for improved
nuisance removal from 1H-MRSI data. Methods: The proposed method uses the resonance …