CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment

J Xiang, VM Tutino, KV Snyder… - American Journal of …, 2014 - Am Soc Neuroradiology
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …

Physical factors effecting cerebral aneurysm pathophysiology

C Sadasivan, DJ Fiorella, HH Woo… - Annals of biomedical …, 2013 - Springer
Many factors that are either blood-, wall-, or hemodynamics-borne have been associated
with the initiation, growth, and rupture of intracranial aneurysms. The distribution of cerebral …

Phase‐contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with …

L Boussel, V Rayz, A Martin… - … in Medicine: An …, 2009 - Wiley Online Library
Evolution of intracranial aneurysms is known to be related to hemodynamic forces such as
wall shear stress (WSS) and maximum shear stress (MSS). Estimation of these parameters …

Hemodynamics and bleb formation in intracranial aneurysms

JR Cebral, M Sheridan… - American Journal of …, 2010 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Intracranial aneurysms with irregular shapes and blebs or
secondary outpouchings have been correlated with increased rupture risk. The purpose of …

The computational fluid dynamics rupture challenge 2013—phase II: variability of hemodynamic simulations in two intracranial aneurysms

P Berg, C Roloff, O Beuing… - Journal of …, 2015 - asmedigitalcollection.asme.org
With the increased availability of computational resources, the past decade has seen a rise
in the use of computational fluid dynamics (CFD) for medical applications. There has been …

Numerical modeling of the flow in intracranial aneurysms: prediction of regions prone to thrombus formation

VL Rayz, L Boussel, MT Lawton… - Annals of biomedical …, 2008 - Springer
The deposition of intralumenal thrombus in intracranial aneurysms adds a risk of thrombo-
embolism over and above that posed by mass effect and rupture. In addition to biochemical …

High shear stress and flow velocity in partially occluded aneurysms prone to recanalization

B Luo, X Yang, S Wang, H Li, J Chen, H Yu, Y Zhang… - Stroke, 2011 - Am Heart Assoc
Background and Purpose—Hemodynamic factors are thought to play an important role in
the initiation, growth, and rupture of cerebral aneurysms. However, the hemodynamic …

Comparison of hemodynamics of intracranial aneurysms between MR fluid dynamics using 3D cine phase-contrast MRI and MR-based computational fluid dynamics

H Isoda, Y Ohkura, T Kosugi, M Hirano, MT Alley… - Neuroradiology, 2010 - Springer
Introduction Hemodynamics is thought to play a very important role in the initiation, growth,
and rupture of intracranial aneurysms. The purpose of our study was to compare …

CFD and PIV analysis of hemodynamics in a growing intracranial aneurysm

M Raschi, F Mut, G Byrne, CM Putman… - … journal for numerical …, 2012 - Wiley Online Library
Hemodynamics is thought to be a fundamental factor in the formation, progression, and
rupture of cerebral aneurysms. Understanding these mechanisms is important to improve …

Identification of hostile hemodynamics and geometries of cerebral aneurysms: a case-control study

BJ Chung, F Mut, CM Putman… - American Journal …, 2018 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Hostile hemodynamic conditions and geometries are
thought to predispose aneurysms for instability and rupture. This study compares stable …