Megalencephaly and hemimegalencephaly: breakthroughs in molecular etiology

GM Mirzaa, A Poduri - … Journal of Medical Genetics Part C …, 2014 - Wiley Online Library
Megalencephaly (MEG) is a developmental disorder characterized by brain overgrowth that
occurs due to either increased number or size of neurons and glial cells. The former may be …

Malformations of cortical development

E Aronica, AJ Becker, R Spreafico - Brain pathology, 2012 - Wiley Online Library
Structural abnormalities of the brain are increasingly recognized in patients that suffer from
pharmacoresistant focal epilepsies by applying high‐resolution imaging techniques. In …

[HTML][HTML] Genes and brain malformations associated with abnormal neuron positioning

JJ Moffat, M Ka, EM Jung, WY Kim - Molecular brain, 2015 - Springer
Neuronal positioning is a fundamental process during brain development. Abnormalities in
this process cause several types of brain malformations and are linked to …

Diffusion tensor imaging and fiber tractography in brain malformations

A Poretti, A Meoded, A Rossi, C Raybaud… - Pediatric …, 2013 - Springer
Diffusion tensor imaging (DTI) is an advanced MR technique that provides qualitative and
quantitative information about the micro-architecture of white matter. DTI and its post …

Development and dysgenesis of the cerebral cortex: malformations of cortical development

C Raybaud, E Widjaja - Neuroimaging Clinics, 2011 - neuroimaging.theclinics.com
The development of the cerebral cortex results from complex and overlapping processes of
cellular proliferation, differentiation, and apoptosis, of migration, and of organization …

Antenatal counselling for prospective parents whose fetus has a neurological anomaly: part 2, risks of adverse outcome in common anomalies

AR Hart, C Vasudevan, PD Griffiths… - … Medicine & Child …, 2022 - Wiley Online Library
After diagnosis of a fetal neurological anomaly, prospective parents want to know the best
and worst‐case scenarios and an estimation of the risk to their infant of having an atypical …

Update on neuroimaging phenotypes of mid-hindbrain malformations

P Jissendi-Tchofo, M Severino, B Nguema-Edzang… - Neuroradiology, 2015 - Springer
Purpose Neuroimaging techniques including structural magnetic resonance imaging (MRI)
and functional positron emission tomography (PET) are useful in categorizing various …

Stereological evaluation of volumetric asymmetry in healthy human cerebellum

N Gocmen-Mas, C Pelin, S Canan, AC Yazici… - Surgical and radiologic …, 2009 - Springer
Objectives Age-related volumetric differences in brain anatomy or volumetric brain analyses
in many disorders are of interest. Delineating the normal anatomical cerebellar volume is of …

Diseases of the Central Nervous System

H Matsuda, E Shimosegawa… - Radiology‐Nuclear …, 2023 - Wiley Online Library
The correct interpretation of neuronuclear images such as those of brain perfusion or
metabolism requires not only identification of the neuroanatomical location of the abnormal …

Aberrant midsagittal fiber tracts in patients with hemimegalencephaly

N Sato, M Ota, A Yagishita, Y Miki… - American journal …, 2008 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In hemimegalencephaly, MR imaging often reveals
midsagittal bandlike structures between the 2 lateral ventricles. To determine whether these …