Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases

RK Burt, Y Loh, W Pearce, N Beohar, WG Barr, R Craig… - Jama, 2008 - jamanetwork.com
Context Stem cell therapy is rapidly developing and has generated excitement and promise
as well as confusion and at times contradictory results in the lay and scientific literature …

[HTML][HTML] Approved and emerging disease modifying therapies on neurodegeneration in multiple sclerosis

M Bross, M Hackett, E Bernitsas - International journal of molecular …, 2020 - mdpi.com
Multiple sclerosis (MS) is an autoimmune, chronic, progressive disease leading to a
combination of inflammation, demyelination, and neurodegeneration throughout the central …

Immunoablation and autologous haemopoietic stem-cell transplantation for aggressive multiple sclerosis: a multicentre single-group phase 2 trial

HL Atkins, M Bowman, D Allan, G Anstee, DL Arnold… - The Lancet, 2016 - thelancet.com
Background Strong immunosuppression, including chemotherapy and immune-depleting
antibodies followed by autologous haemopoietic stem-cell transplantation (aHSCT), has …

[HTML][HTML] The current standing of autologous haematopoietic stem cell transplantation for the treatment of multiple sclerosis

AG Willison, T Ruck, G Lenz, HP Hartung… - Journal of neurology, 2022 - Springer
Autologous haematopoietic stem cell transplantation (aHSCT) is gaining traction as a
valuable treatment option for patients affected by severe multiple sclerosis (MS), particularly …

Autologous haematopoietic stem-cell transplantation in multiple sclerosis

G Mancardi, R Saccardi - The Lancet Neurology, 2008 - thelancet.com
Intense immunosuppression followed by autologous haematopoietic stem-cell
transplantation has been assessed over the past few years as a possible new therapeutic …

Updating the mild encephalitis hypothesis of schizophrenia

K Bechter - Progress in Neuro-Psychopharmacology and …, 2013 - Elsevier
Schizophrenia seems to be a heterogeneous disorder. Emerging evidence indicates that
low level neuroinflammation (LLNI) may not occur infrequently. Many infectious agents with …

[HTML][HTML] Methemoglobin is an endogenous toll-like receptor 4 ligand—relevance to subarachnoid hemorrhage

MS Kwon, SK Woo, DB Kurland, SH Yoon… - International journal of …, 2015 - mdpi.com
Neuroinflammation is a well-recognized consequence of subarachnoid hemorrhage (SAH),
and may be responsible for important complications of SAH. Signaling by Toll-like receptor 4 …

[HTML][HTML] Dynamics of inflammatory and neurodegenerative biomarkers after autologous hematopoietic stem cell transplantation in multiple sclerosis

J Ruder, G Dinner, A Maceski… - International journal of …, 2022 - mdpi.com
Autologous hematopoietic stem cell transplantation (aHSCT) is a highly efficient treatment of
multiple sclerosis (MS), and hence it likely normalizes pathological and/or enhances …

[HTML][HTML] Non-immunogenic induced pluripotent stem cells, a promising way forward for allogenic transplantations for neurological disorders

HR Frederiksen, U Doehn, P Tveden-Nyborg… - Frontiers in Genome …, 2021 - frontiersin.org
Neurological disorder is a general term used for diseases affecting the function of the brain
and nervous system. Those include a broad range of diseases from developmental …

Brain atrophy after bone marrow transplantation for treatment of multiple sclerosis

H Lee, S Narayanan, RA Brown… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: A cohort of patients with poor-prognosis multiple sclerosis (MS) underwent
chemotherapy-based immune ablation followed by immune reconstitution with an …