White matter hyperintensities are frequent on neuroimaging of older people and are a key
feature of cerebral small vessel disease. They are commonly attributed to chronic …

CTP has a growing role in evaluating stroke. It can be performed immediately following
NCCT and has advantages of accessibility and speed. Differentiation of salvageable …

Alzheimer's disease (AD) is a leading cause of death and disability among older adults.
Modifiable vascular risk factors for AD (VRF) include obesity, hypertension, type 2 diabetes …

Introduction Cerebral small vessel disease (SVD) contributes to dementia and disability in
the elderly, and may negatively affect stroke outcomes. We aimed to evaluate to what extent …

Background Leukoaraiosis is associated with impaired cerebral perfusion, but the effect of
individual and combined small-vessel disease (SVD) features on white matter perfusion is …

Aim-White matter hyperintensities (WMH) and lacunes were important features of cerebral
small vessel disease (CSVD), which contributes to 25% of ischemic strokes and 45% of …

Background. The main theory underlying the use of perfusion imaging in acute ischemic
stroke is the presence of a hypoperfused volume of the brain downstream of an occluded …

Cerebral small vessel disease (SVD) is common in older people and is associated with
lacunar stroke, white matter hyperintensities (WMH) and vascular cognitive impairment …

Abnormal reductions in cortical cerebral blood flow (CBF) have been identified in subcortical
vascular cognitive impairment (SVCI). However, little is known about the pattern of CBF …

Small vessel disease (SVD) is responsible for brain chronic circular disorder, and accounts
for 20%–30% cases of ischemic stroke as well as cerebral hemorrhage, and to a great …