Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …

PY Wen, M Weller, EQ Lee, BM Alexander… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Advances in neuro-oncology imaging

KJ Langen, N Galldiks, E Hattingen… - Nature Reviews …, 2017 - nature.com
Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key …

Cerebral gliomas: diffusional kurtosis imaging analysis of microstructural differences

P Raab, E Hattingen, K Franz, FE Zanella… - Radiology, 2010 - pubs.rsna.org
Purpose To characterize the non-Gaussian diffusion patterns of cerebral glioma
microstructure with respect to the different glioma grades by using a new method called …

Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast …

RF Barajas Jr, JS Chang, MR Segal, AT Parsa… - Radiology, 2009 - pubs.rsna.org
Purpose To investigate whether cerebral blood volume (CBV), peak height (PH), and
percentage of signal intensity recovery (PSR) measurements derived from the results of T2 …

Advanced MRI and PET imaging for assessment of treatment response in patients with gliomas

FG Dhermain, P Hau, H Lanfermann… - The Lancet …, 2010 - thelancet.com
Imaging techniques are important for accurate diagnosis and follow-up of patients with
gliomas. T1-weighted MRI, with or without gadolinium, is the gold standard method …

[HTML][HTML] The correlation between apparent diffusion coefficient and tumor cellularity in patients: a meta-analysis

L Chen, M Liu, J Bao, Y Xia, J Zhang, L Zhang… - PloS one, 2013 - journals.plos.org
Objective To perform a meta-analysis exploring the correlation between the apparent
diffusion coefficient (ADC) and tumor cellularity in patients. Materials and Methods We …

Imaging of intratumoral heterogeneity in high-grade glioma

LS Hu, A Hawkins-Daarud, L Wang, J Li, KR Swanson - Cancer letters, 2020 - Elsevier
Abstract High-grade glioma (HGG), and particularly Glioblastoma (GBM), can exhibit
pronounced intratumoral heterogeneity that confounds clinical diagnosis and management …

[HTML][HTML] Integration of machine learning and mechanistic models accurately predicts variation in cell density of glioblastoma using multiparametric MRI

N Gaw, A Hawkins-Daarud, LS Hu, H Yoon, L Wang… - Scientific reports, 2019 - nature.com
Glioblastoma (GBM) is a heterogeneous and lethal brain cancer. These tumors are followed
using magnetic resonance imaging (MRI), which is unable to precisely identify tumor cell …

Hot spots in dynamic18FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas

M Kunz, N Thon, S Eigenbrod, C Hartmann… - Neuro …, 2011 - academic.oup.com
Molecular imaging studies have recently found inter-and intratumoral heterogeneity in World
Health Organization (WHO) grade II gliomas. A correlative analysis with tumor histology …

Regional variation in histopathologic features of tumor specimens from treatment-naive glioblastoma correlates with anatomic and physiologic MR Imaging

RF Barajas Jr, JJ Phillips, R Parvataneni… - Neuro …, 2012 - academic.oup.com
Histopathologic evaluation of glioblastoma multiforme (GBM) at initial diagnosis is typically
performed on tissue obtained from regions of contrast enhancement (CE) as depicted on …