Importance Multiple myeloma is a hematologic malignancy characterized by presence of
abnormal clonal plasma cells in the bone marrow, with potential for uncontrolled growth …

Balloon kyphoplasty and percutaneous vertebroplasty are relatively recent procedures in the
treatment of painful vertebral fractures. There are, however, still some uncertainties about …

International Myeloma Working Group Recommendations for the Treatment of Multiple
Myeloma–Related Bone Disease - PMC Back to Top Skip to main content NIH NLM Logo …

BACKGROUND: Vertebroplasty (VP) and kyphoplasty (KP) are routinely used to treat
vertebral body compression fractures (VCFs) resulting from osteoporosis or vertebral body …

Supportive care plays an increasingly important role in the modern management of multiple
myeloma. While modern treatments have significantly prolonged overall and progression …

Background Cancers that metastasize to the spine and primary cancers such as multiple
myeloma can result in vertebral compression fractures or instability. Conservative strategies …

Abstract Background Bisphosphonates (BPs) prevent, reduce, and delay multiple myeloma
(MM)-related skeletal complications. Intravenous pamidronate and zoledronic acid, and oral …

Purpose Percutaneous vertebroplasty (PVP) is a common procedure in spine surgery. Bone
cement leakage is the most common complication related to this procedure. The purpose of …

Introduction Management of metastatic spine disease is quite complex. Advances in
research have allowed surgeons and physicians to better provide chemotherapeutic agents …

Primary malignant tumors of the spine account for less than 5% of primary bone tumors.
Data from the SEER program suggest that the most common bone sarcomas are …