Nimodipine reappraised: an old drug with a future

AP Carlson, D Hänggi, RL Macdonald… - Current …, 2020 - ingentaconnect.com
Nimodipine is a dihydropyridine calcium channel antagonist that blocks the flux of
extracellular calcium through L-type, voltage-gated calcium channels. While nimodipine is …

[HTML][HTML] Cerebral autoregulation in subarachnoid hemorrhage

D Lidington, H Wan, SS Bolz - Frontiers in neurology, 2021 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a devastating stroke subtype with a high rate of
mortality and morbidity. The poor clinical outcome can be attributed to the biphasic course of …

Endovascular treatment of cerebral vasospasm after subarachnoid hemorrhage: more is more

R Jabbarli, D Pierscianek, R Rölz… - Neurology, 2019 - AAN Enterprises
Objective Delayed cerebral ischemia (DCI) is strongly associated with poor outcome after
subarachnoid hemorrhage (SAH). Cerebral vasospasm is a major contributor to DCI and …

[HTML][HTML] Blood pressure affects the early CT perfusion imaging in patients with aSAH reflecting early disturbed autoregulation

BB Hofmann, DM Donaldson, I Fischer, C Karadag… - Neurocritical Care, 2023 - Springer
Background Early computed tomography perfusion (CTP) is frequently used to predict
delayed cerebral ischemia following aneurysmatic subarachnoid hemorrhage (aSAH) …

Current options for the management of aneurysmal subarachnoid hemorrhage-induced cerebral vasospasm: a comprehensive review of the literature

G Dabus, RG Nogueira - Interventional neurology, 2013 - karger.com
Objectives: Cerebral vasospasm is one of the leading causes of morbi-mortality following
aneurysmal subarachnoid hemorrhage. The aim of this article is to discuss the current status …

Treatment of cerebral vasospasm following aneurysmal subarachnoid haemorrhage: a systematic review and meta-analysis

G Boulouis, MA Labeyrie, J Raymond… - European …, 2017 - Springer
Objectives To examine the clinical outcome of aneurysmal subarachnoid haemorrhage
(aSAH) patients exposed to cerebral vasospasm (CVS)-targeted treatments in a meta …

A review of delayed ischemic neurologic deficit following aneurysmal subarachnoid hemorrhage: historical overview, current treatment, and pathophysiology

YZ Al-Tamimi, NM Orsi, AC Quinn… - World neurosurgery, 2010 - Elsevier
Delayed ischemic neurologic deficit (DIND) is a serious and poorly understood complication
of aneurysmal subarachnoid hemorrhage. Although advances in treatment have improved …

[HTML][HTML] Endovascular rescue treatment for delayed cerebral ischemia after subarachnoid hemorrhage is safe and effective

M Weiss, C Conzen, M Mueller, M Wiesmann… - Frontiers in …, 2019 - frontiersin.org
Background: The implementation of rescue efforts for delayed cerebral ischemia after
aneurysmal subarachnoid hemorrhage remains largely empirical for a lack of supporting …

Complication rate of intraarterial treatment of severe cerebral vasospasm after subarachnoid hemorrhage with nimodipine and percutaneous transluminal balloon …

D Adami, J Berkefeld, J Platz, J Konczalla… - Journal of …, 2019 - Elsevier
Background and purpose Delayed cerebral ischemia (DCI) is a complication of aneurysmal
subarachnoid hemorrhage (SAH). Arterial cerebral vasospasm (CVS) is discussed as the …

[HTML][HTML] Inhaled nitric oxide treatment for aneurysmal SAH patients with delayed cerebral ischemia

C Fung, WJ Z'Graggen, SM Jakob, J Gralla… - Frontiers in …, 2022 - frontiersin.org
Background We demonstrated experimentally that inhaled nitric oxide (iNO) dilates
hypoperfused arterioles, increases tissue perfusion, and improves neurological outcome …