Today, children are surviving pediatric cancer at unprecedented rates, making it one of
modern medicine's true success stories. However, we are increasingly becoming aware of …

Survival rates of children with cancer are steadily increasing. This urges our attention to
neurocognitive and psychiatric outcomes, as these can markedly influence the quality of life …

In recent years, graph theoretical analyses of neuroimaging data have increased our
understanding of the organization of large-scale structural and functional brain networks …

Chemotherapy Pharmacodynamics and Neuroimaging and Neurocognitive Outcomes in
Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia - PMC Back to Top Skip to …

Purpose CNS-directed chemotherapy (CT) and cranial radiotherapy (CRT) for childhood
acute lymphoblastic leukemia or lymphoma have various neurotoxic properties. This study …

BACKGROUND: To extend investigation beyond global cognitive measures prevalent in the
literature, this study examined attention and working memory (WM) abilities of survivors of …

Object: Magnetic resonance fingerprinting (MRF) allows rapid, simultaneous mapping of T1
and T2 relaxation times and may be an important diagnostic tool to measure tissue …

Introduction Survival rates for children with acute lymphoblastic leukemia (ALL) approach
95%. At the same time, there is growing concern that chemotherapy causes alterations in …

Objective Using multidisciplinary treatment modalities the majority of children with cancer
can be cured but we are increasingly faced with therapy-related toxicities. We studied brain …

Acute lymphoblastic leukemia (ALL) is associated with long-term, progressive cognitive
deficits and white matter injury. We measured global and regional white and gray matter as …