Multiple sclerosis is a major cause of neurological disability, which accrues predominantly
during progressive forms of the disease. Although development of multifocal inflammatory …

A first-ever spinal cord imaging meeting was sponsored by the International Spinal
Research Trust and the Wings for Life Foundation with the aim of identifying the current state …

Background A recent meeting of international imaging experts sponsored by the
International Spinal Research Trust (ISRT) and the Wings for Life Foundation identified 5 …

Proton magnetic resonance spectroscopy (1 H MRS) has been applied to numerous clinical
studies, especially for neurological disorders. This technique can non-invasively evaluate …

Amyotrophic lateral sclerosis (ALS) is the most common adult onset motor neuron disease
with no effective disease modifying therapies at present. Spinal cord degeneration is a …

Research advances support the idea that excessive activation of the glutamatergic pathway
plays an important part in the pathophysiology of multiple sclerosis. Beyond the well …

Proton magnetic resonance spectroscopy (1 H-MRS) offers a growing variety of methods for
querying potential diagnostic biomarkers of multiple sclerosis in living central nervous …

The spinal cord is a clinically important site that is affected by pathological changes in most
patients with multiple sclerosis; however, imaging of the spinal cord with conventional MRI …

Magnetic resonance spectroscopy enables insight into the chemical composition of spinal
cord tissue. However, spinal cord magnetic resonance spectroscopy has rarely been …

Spinal neurodegeneration is an important determinant of disability progression in patients
with primary progressive multiple sclerosis. Advanced imaging techniques, such as single …