Activatable T 1 and T 2 Magnetic Resonance Imaging Contrast Agents

C Tu, EA Osborne, AY Louie - Annals of biomedical engineering, 2011 - Springer
Magnetic resonance imaging (MRI) has become one of the most important diagnosis tools
available in medicine. Typically MRI is not capable of sensing biochemical activities …

Main applications of hybrid PET‐MRI contrast agents: a review

A Kiani, A Esquevin, N Lepareur… - Contrast media & …, 2016 - Wiley Online Library
In medical imaging, the continuous quest to improve diagnostic performance and optimize
treatment strategies has led to the use of combined imaging modalities. Positron emission …

[BOOK][B] Handbook on the Physics and Chemistry of Rare Earths: Including Actinides

JCG Bunzli, VK Pecharsky - 2016 - books.google.com
Handbook on the Physics and Chemistry of Rare Earths: Including Actinides is a continuous
series of books covering all aspects of rare earth science, including chemistry, life sciences …

On the synthesis of 1, 4, 7-tris (tert-butoxycarbonylmethyl)-1, 4, 7, 10-tetraazacyclododecane

B Jagadish, GL Brickert-Albrecht, GS Nichol, EA Mash… - Tetrahedron letters, 2011 - Elsevier
1, 4, 7-Tris (tert-butoxycarbonylmethyl)-1, 4, 7, 10-tetraazacyclododecane is widely used as
an intermediate in the preparation of medically important DO3A and DOTA metal chelators …

Novel nanomedicine with a chemical-exchange saturation transfer effect for breast cancer treatment in vivo

Y Jia, C Wang, J Zheng, G Lin, D Ni, Z Shen… - Journal of …, 2019 - Springer
Background Nanomedicine is a promising new approach to cancer treatment that avoids the
disadvantages of traditional chemotherapy and improves therapeutic indices. However, the …

Bioresponsive probes for molecular imaging: concepts and in vivo applications

SMJ van Duijnhoven, MS Robillard… - Contrast Media & …, 2015 - Wiley Online Library
Molecular imaging is a powerful tool to visualize and characterize biological processes at
the cellular and molecular level in vivo. In most molecular imaging approaches, probes are …

Optimization of rapid acquisition with relaxation enhancement (RARE) pulse sequence parameters for 19F‐MRI studies

A Mastropietro, E De Bernardi… - Journal of Magnetic …, 2014 - Wiley Online Library
Purpose To optimize signal‐to‐noise ratio (SNR) in fast spin echo (rapid acquisition with
relaxation enhancement [RARE]) sequences and to improve sensitivity in 19F magnetic …

Importance of ligand design in lanthanide azamacrocyclic complexes relevant to biomedical applications

R Tripier, G Tircsó, C Platas-Iglesias… - Handbook on the Physics …, 2022 - Elsevier
In this chapter, we analyze ligand structural features necessary for the design of stable and
inert lanthanide complexes for use in biomedical applications. In the first sections of the …

Activatable interpolymer complex-superparamagnetic iron oxide nanoparticles as magnetic resonance contrast agents sensitive to oxidative stress

E Yoo, HA Cheng, LE Nardacci, DJ Beaman… - Colloids and Surfaces B …, 2017 - Elsevier
Magnetic resonance contrast agents that can be activated in response to specific triggers
hold potential as molecular biosensors that may be of great utility in non-invasive disease …

Mechanistic Studies of Gd3+‐Based MRI Contrast Agents for Zn2+ Detection: Towards Rational Design

CS Bonnet, F Caillé, A Pallier, JF Morfin… - … A European Journal, 2014 - Wiley Online Library
A series of novel pyridine‐based Gd3+ complexes have been prepared and studied as
potential MRI contrast agents for Zn2+ detection. By independent assessment of molecular …