Animal models make an important contribution to our basic understanding of the
pathobiology of human brain aneurysms, are indispensable in testing novel treatment …

Introduction: The number of microsurgical clippings of cerebral aneurysms is continuously
decreasing. This will lead to fewer possibilities for practical training in aneurysm surgery …

Object Flow diverters (FDs) are increasingly used to treat complex intracranial aneurysms,
but preclinical studies that could guide clinical applications are lacking. The authors …

BACKGROUND AND PURPOSE: FDs are new intracranial stents designed to occlude
aneurysms while preserving flow to jailed arterial branches. We tested this fundamental …

Recent findings have demonstrated that amniotic fluid cells are an interesting and potential
source of mesenchymal stem cells (MSCs). In this study, we isolated MSCs from canine …

Background. Most available large animal extracranial aneurysm models feature healthy non-
degenerated aneurysm pouches with stable long-term follow-ups and extensive healing …

Objective Flow diverters (FDs) are increasingly used to treat difficult intracranial aneurysms.
The objective of this study was to test whether treatment challenges posed by giant curved …

Purpose Several different training environments for practicing neurointerventional
procedures have been realized in silico, in vitro, and in vivo. We seek to replace animal …

BACKGROUND AND PURPOSE: Rabbit elastase-induced saccular aneurysms have been
commonly used for preclinical testing of endovascular devices, including flow diverters …

Background Animal experimental studies are crucial for the development of endovascular
devices and embolization techniques for intracranial aneurysms. The aim of the study was to …