Current approaches to the management of brain metastases
JH Suh, R Kotecha, ST Chao, MS Ahluwalia… - Nature reviews Clinical …, 2020 - nature.com
Brain metastases are a very common manifestation of cancer that have historically been
approached as a single disease entity given the uniform association with poor clinical …
approached as a single disease entity given the uniform association with poor clinical …
Response assessment criteria for brain metastases: proposal from the RANO group
CNS metastases are the most common cause of malignant brain tumours in adults.
Historically, patients with brain metastases have been excluded from most clinical trials, but …
Historically, patients with brain metastases have been excluded from most clinical trials, but …
Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases
A recent meeting was held on March 22, 2019, among the FDA, clinical scientists,
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …
[HTML][HTML] Diagnosis and management of radiation necrosis in patients with brain metastases
The use of radiotherapy, either in the form of stereotactic radiosurgery (SRS) or whole-brain
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …
Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases?
RJ Colaco, P Martin, HM Kluger, BY James… - Journal of …, 2016 - thejns.org
OBJECT Radiation necrosis (RN), or its imaging equivalent, treatment-related imaging
changes (TRIC), is an inflammatory reaction to high-dose radiation in the brain. The authors …
changes (TRIC), is an inflammatory reaction to high-dose radiation in the brain. The authors …
Timing and type of immune checkpoint therapy affect the early radiographic response of melanoma brain metastases to stereotactic radiosurgery
BACKGROUND Growing evidence suggests that immunotherapy and radiation therapy can
be synergistic in the treatment of cancer. This study was performed to determine the effect of …
be synergistic in the treatment of cancer. This study was performed to determine the effect of …
Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: response, progression, and pseudoprogression
N Galldiks, M Kocher, G Ceccon, JM Werner… - Neuro …, 2020 - academic.oup.com
The advent of immunotherapy using immune checkpoint inhibitors (ICIs) and targeted
therapy (TT) has dramatically improved the prognosis of various cancer types. However …
therapy (TT) has dramatically improved the prognosis of various cancer types. However …
Brain metastases: neuroimaging
WB Pope - Handbook of clinical neurology, 2018 - Elsevier
Magnetic resonance imaging (MRI) is the cornerstone for evaluating patients with brain
masses such as primary and metastatic tumors. Important challenges in effectively detecting …
masses such as primary and metastatic tumors. Important challenges in effectively detecting …
[PDF][PDF] Stereotactic radiosurgery for treatment of brain metastases
However, the number of randomized clinical trials performed to evaluate the therapeutic
options for brain metastases is still limited, leaving evidence-based management of this …
options for brain metastases is still limited, leaving evidence-based management of this …
Distinguishing true progression from radionecrosis after stereotactic radiation therapy for brain metastases with machine learning and radiomics
Purpose Treatment effect or radiation necrosis after stereotactic radiosurgery (SRS) for brain
metastases is a common phenomenon often indistinguishable from true progression …
metastases is a common phenomenon often indistinguishable from true progression …
