Malformations of cortical development are a group of rare disorders commonly manifesting
with developmental delay, cerebral palsy or seizures. The neurological outcome is …

One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

BACKGROUND AND PURPOSE: Although microcephaly is the most prominent feature of
congenital Zika syndrome, a spectrum with less severe cases is starting to be recognized …

The most frequently asked questions that confront the fetal medicine trainee/expert on a
daily basis are “Is the finding real or merely an artifact?” and “Is the diagnosis correct?” …

Background Congenital Zika virus (ZIKV) infection can be detected in both the presence and
absence of microcephaly and manifests as a number of signs and symptoms that are …

Objective To provide new insights into the FOXG1-related clinical and imaging phenotypes
and refine the phenotype-genotype correlation in FOXG1 syndrome. Methods We analyzed …

Cell division terminates with cytokinesis and cellular separation. Autosomal-recessive
primary microcephaly (MCPH) is a neurodevelopmental disorder characterized by a …

The development of the cerebral cortex results from complex and overlapping processes of
cellular proliferation, differentiation, and apoptosis, of migration, and of organization …

Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders –
RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY - Abstract - Europe PMC Sign in …

In this review, we discuss molecular and cellular mechanisms important for the function of
neuronal progenitors during development, revealed by their perturbation in different cortical …