[HTML][HTML] Neuroprotective agents in the management of glaucoma
Glaucoma is an optic neuropathy, specifically a neurodegenerative disease characterized
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …
by loss of retinal ganglion cells (RGCs) and their axons. The pathogenesis of RGC loss in …
Glaucoma and the brain: trans-synaptic degeneration, structural change, and implications for neuroprotection
M Lawlor, H Danesh-Meyer, LA Levin… - Survey of …, 2018 - Elsevier
A recent hypothesis to enter the literature suggests that glaucoma is a neurodegenerative
disease. The basis for this has been the finding of central nervous system changes in …
disease. The basis for this has been the finding of central nervous system changes in …
[HTML][HTML] Glaucoma: a degenerative optic neuropathy related to neuroinflammation?
S Mélik Parsadaniantz, A Réaux-le Goazigo… - Cells, 2020 - mdpi.com
Glaucoma is one of the leading causes of irreversible blindness in the world and remains a
major public health problem. To date, incomplete knowledge of this disease's …
major public health problem. To date, incomplete knowledge of this disease's …
[HTML][HTML] Transneuronal degeneration in the brain during glaucoma
M You, R Rong, Z Zeng, X Xia, D Ji - Frontiers in aging neuroscience, 2021 - frontiersin.org
The death of retinal ganglion cells (RGCs) is a key factor in the pathophysiology of all types
of glaucoma, but the mechanism of pathogenesis of glaucoma remains unclear. RGCs are a …
of glaucoma, but the mechanism of pathogenesis of glaucoma remains unclear. RGCs are a …
[HTML][HTML] Structural brain abnormalities in patients with primary open-angle glaucoma: a study with 3T MR imaging
Purpose.: Weexamined changes of the central nervous system in patients with advanced
primary open-angle glaucoma (POAG). Methods.: The clinical observational study included …
primary open-angle glaucoma (POAG). Methods.: The clinical observational study included …
Glaucoma as a neurodegenerative disease
HV Danesh-Meyer, LA Levin - Journal of Neuro-Ophthalmology, 2015 - journals.lww.com
Background: The primary pathophysiological feature of glaucoma is a progressive optic
neuropathy with characteristic morphological changes of the optic disc and risk factors of …
neuropathy with characteristic morphological changes of the optic disc and risk factors of …
[HTML][HTML] In vivo Probabilistic Structural Atlas of the Inferior and Superior Colliculi, Medial and Lateral Geniculate Nuclei and Superior Olivary Complex in Humans …
MG García-Gomar, C Strong, N Toschi… - Frontiers in …, 2019 - frontiersin.org
Despite extensive neuroimaging research of primary sensory cortices involved in auditory
and visual functions, subcortical structures within these domains, such as the inferior and …
and visual functions, subcortical structures within these domains, such as the inferior and …
Selective reduction of fMRI responses to transient achromatic stimuli in the magnocellular layers of the LGN and the superficial layer of the SC of early glaucoma …
Glaucoma is now viewed not just a disease of the eye but also a disease of the brain. The
prognosis of glaucoma critically depends on how early the disease can be detected …
prognosis of glaucoma critically depends on how early the disease can be detected …
New strategies for neuroprotection in glaucoma, a disease that affects the central nervous system
C Nucci, R Russo, A Martucci, C Giannini… - European Journal of …, 2016 - Elsevier
Glaucoma is a disease where retinal ganglion cells (RGC) are specifically affected though a
number of evidences endorse the hypothesis that glaucoma is a neuro-degenerative …
number of evidences endorse the hypothesis that glaucoma is a neuro-degenerative …
Damage of the lateral geniculate nucleus in MS: assessing the missing node of the visual pathway
A Papadopoulou, L Gaetano, A Pfister, A Altermatt… - Neurology, 2019 - AAN Enterprises
Objective To study if the thalamic lateral geniculate nucleus (LGN) is affected in multiple
sclerosis (MS) due to anterograde degeneration from optic neuritis (ON) or retrograde …
sclerosis (MS) due to anterograde degeneration from optic neuritis (ON) or retrograde …