[HTML][HTML] SyMRI of the brain: rapid quantification of relaxation rates and proton density, with synthetic MRI, automatic brain segmentation, and myelin measurement

A Hagiwara, M Warntjes, M Hori, C Andica… - Investigative …, 2017 - journals.lww.com
Conventional magnetic resonance images are usually evaluated using the image signal
contrast between tissues and not based on their absolute signal intensities. Quantification of …

Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics

AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …

[HTML][HTML] Myelin Measurement: Comparison Between Simultaneous Tissue Relaxometry, Magnetization Transfer Saturation Index, and T1w/T2w Ratio Methods

A Hagiwara, M Hori, K Kamagata, M Warntjes… - Scientific reports, 2018 - nature.com
Magnetization transfer (MT) imaging has been widely used for estimating myelin content in
the brain. Recently, two other approaches, namely simultaneous tissue relaxometry of R1 …

[HTML][HTML] Linearity, bias, intrascanner repeatability, and interscanner reproducibility of quantitative multidynamic multiecho sequence for rapid simultaneous …

A Hagiwara, M Hori, J Cohen-Adad… - Investigative …, 2019 - journals.lww.com
Objectives The aim of this study was to evaluate the linearity, bias, intrascanner
repeatability, and interscanner reproducibility of quantitative values derived from a …

Clinical feasibility of synthetic MRI in multiple sclerosis: a diagnostic and volumetric validation study

T Granberg, M Uppman, F Hashim… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Quantitative MR imaging techniques are gaining interest
as methods of reducing acquisition times while additionally providing robust measurements …

Improving the quality of synthetic FLAIR images with deep learning using a conditional generative adversarial network for pixel-by-pixel image translation

A Hagiwara, Y Otsuka, M Hori… - American journal …, 2019 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Synthetic FLAIR images are of lower quality than
conventional FLAIR images. Here, we aimed to improve the synthetic FLAIR image quality …

Validation of rapid magnetic resonance myelin imaging in multiple sclerosis

R Ouellette, G Mangeat, I Polyak, M Warntjes… - Annals of …, 2020 - Wiley Online Library
Objective Magnetic resonance imaging (MRI) is essential for multiple sclerosis diagnostics
but is conventionally not specific to demyelination. Myelin imaging is often hampered by …

[HTML][HTML] Age-related changes in relaxation times, proton density, myelin, and tissue volumes in adult brain analyzed by 2-dimensional quantitative synthetic magnetic …

A Hagiwara, K Fujimoto, K Kamagata… - Investigative …, 2021 - journals.lww.com
Objectives Quantitative synthetic magnetic resonance imaging (MRI) enables the
determination of fundamental tissue properties, namely, T1 and T2 relaxation times and …

A comparison of intracranial volume estimation methods and their cross‐sectional and longitudinal associations with age

S Nerland, TS Stokkan, KN Jørgensen… - Human Brain …, 2022 - Wiley Online Library
Intracranial volume (ICV) is frequently used in volumetric magnetic resonance imaging (MRI)
studies, both as a covariate and as a variable of interest. Findings of associations between …

Review of synthetic MRI in pediatric brains: Basic principle of MR quantification, its features, clinical applications, and limitations

C Andica, A Hagiwara, M Hori, K Kamagata… - Journal of …, 2019 - Elsevier
Quantitative magnetic resonance imaging (MRI) with multislice, multi-echo, and multi-delay
acquisition enables simultaneous quantification of R 1 and R 2 relaxation rates, proton …