Clinical trials in progressive multiple sclerosis: lessons learned and future perspectives

D Ontaneda, RJ Fox, J Chataway - The Lancet Neurology, 2015 - thelancet.com
Progressive multiple sclerosis is characterised clinically by the gradual accrual of disability
independent of relapses and can occur with disease onset (primary progressive) or can be …

[HTML][HTML] Harmonization of brain diffusion MRI: Concepts and methods

MS Pinto, R Paolella, T Billiet, P Van Dyck… - Frontiers in …, 2020 - frontiersin.org
MRI diffusion data suffers from significant inter-and intra-site variability, which hinders multi-
site and/or longitudinal diffusion studies. This variability may arise from a range of factors …

How are age-related differences in sleep quality associated with health outcomes? An epidemiological investigation in a UK cohort of 2406 adults

A Gadie, M Shafto, Y Leng, RA Kievit - BMJ open, 2017 - bmjopen.bmj.com
Objectives To examine age-related differences in self-reported sleep quality and their
associations with health outcomes across four domains: physical health, cognitive health …

[HTML][HTML] Diffusion MRI of white matter microstructure development in childhood and adolescence: Methods, challenges and progress

CK Tamnes, DR Roalf, AL Goddings, C Lebel - Developmental cognitive …, 2018 - Elsevier
Diffusion magnetic resonance imaging (dMRI) continues to grow in popularity as a useful
neuroimaging method to study brain development, and longitudinal studies that track the …

A purely confirmatory replication study of structural brain-behavior correlations

W Boekel, EJ Wagenmakers, L Belay, J Verhagen… - cortex, 2015 - Elsevier
A recent 'crisis of confidence'has emerged in the empirical sciences. Several studies have
suggested that questionable research practices (QRPs) such as optional stopping and …

[HTML][HTML] Microstructural and functional plasticity following repeated brain stimulation during cognitive training in older adults

D Antonenko, AE Fromm, F Thams, U Grittner… - Nature …, 2023 - nature.com
The combination of repeated behavioral training with transcranial direct current stimulation
(tDCS) holds promise to exert beneficial effects on brain function beyond the trained task …

Inter-site and inter-scanner diffusion MRI data harmonization

H Mirzaalian, L Ning, P Savadjiev, O Pasternak… - NeuroImage, 2016 - Elsevier
We propose a novel method to harmonize diffusion MRI data acquired from multiple sites
and scanners, which is imperative for joint analysis of the data to significantly increase …

A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis

HP Müller, MR Turner, J Grosskreutz… - Journal of Neurology …, 2016 - jnnp.bmj.com
Objective Damage to the cerebral tissue structural connectivity associated with amyotrophic
lateral sclerosis (ALS), which extends beyond the motor pathways, can be visualised by …

[HTML][HTML] A watershed model of individual differences in fluid intelligence

RA Kievit, SW Davis, J Griffiths, MM Correia… - Neuropsychologia, 2016 - Elsevier
Fluid intelligence is a crucial cognitive ability that predicts key life outcomes across the
lifespan. Strong empirical links exist between fluid intelligence and processing speed on the …

Toward precision and reproducibility of diffusion tensor imaging: a multicenter diffusion phantom and traveling volunteer study

EM Palacios, AJ Martin, MA Boss… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Precision medicine is an approach to disease diagnosis,
treatment, and prevention that relies on quantitative biomarkers that minimize the variability …